Direction: Identify and explain the etiology of chromosomal abnormality in the given karyotype. KARYOTYPE 1:

Q: what is the diagnosis of Chronic granulomatous disease (CGD) and explain the genetic mechanism…

A: Bridges-Good syndrome is another name for chronic granulomatous disease (CGD). The distinctive…

Q: D. A. B. 10. C. Familial hypercholesterolemia is the most common genetic cause of heart disease. It…

A: We need to understand the basic concepts of genetics and also consider how these traits are…

Q: What is a tumour marker? How are tumour markers detected in the body and can they be used…

A: A tumour is an abnormal growth of cells that can occur in any part of the body. Tumours can be…

Q: Explain the process of adenoma or polyp ?

A: The suffix "-oma" is used in medical terminologies to indicate cancer. Adenoma refers to the…

Q: Write the name of lysosomal storage disorders.

A: Lysosomal storage disorder are also known as sphingolipidoses, in which sphingolipids are…

Q: List seven observations that suggest a disease may have a genetic component.

A: The diagnosis of a genetic disorder is  essential for an extensive clinical examination and made up…

Q: Explain the multi hit approach to colorectal cancer regarding the pathways CIN chromosomal…

A: The so-called "adenoma-carcinoma sequence" describes the progression of colorectal malignancies…

Q: C. Give the genotypic and phenotypic ratios  1. Hemophilia is a disease caused by a gene found on…

A: Genetics deals with the  inheritance of characters across the generations. The dominant characters…

Q: Chronic Myelogenous Leukemia (CML) -Briefly describe the disease and provide the most common…

A: Leukemia  It is the group of malignant disorder. It affects the blood and blood forming tissues of…

Q: Describe both the primary gene or protein defect and the resulting phenotype for the following…

A: A)Cystic fibrosis is an autosomal recessive disease.It is a progressive disease and requires daily…

Q: Select two of the following diseases and discuss cause, predisposing factors and identify if it is…

A: 2) Cystic fibrosis A genetic (inherited) condition known as cystic fibrosis (CF) results in the…

Q: Define: Recombinant DNA:

A: A DNA fragment is cut from foreign DNA using restriction enzymes (an enzyme used to cut DNA) and the…

Q: Type of Inheritance: Explanation: Punnett Square:

A: Pedigree is the familal representation of a particular trait.  Half filled symbols depict the…

Q: List seven factors that suggest a disease may have a genetic component.

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Give an examples of genetic diseases.

A: A genetic disorder or genetic disease is a condition that occurs because of any defect or change in…

Q: In the autosomal dominant/complete dominant form of the disease, in a cross between a homozygous…

A: When a single copy of a dominant gene is sufficient to manifest a specific trait or disease, the…

Q: Determine the genotype for each phenotype using the Information provided: SQUARE shape (S) is…

A: *Phenotypes means the traits that an individual contains can be easily observable  * Ex: colour,…

Q: Explain why metastasis can lead to multiplesecondary tumors in different sites.

A: When there is some mutation that occurs in the DNA of any cell that leads to abnormal and…

Q: What is the difference between a lesion and an ablation?

A: Cells are the structural and fundamental units of life. Cells that possess similarity in structure…

Q: Explain an example  of single-nucleotide polymorphism (SNP) associated with disease.

A: Answer- Single nucleotide polymorphism is the DNA sequence variation at the single site.

Q: 3 4. 11 12 13 14 15 18 19 21 22 Y 2. 20

A: Karyotyping is the process by which photographs of chromosomes are taken in order to determine the…

Q: Explain the involvement of viruses in cancer and congenitalinfections.

A: Step 1 Viruses are an ultramicroscopic nucleoprotein entity that becomes active only inside a living…

Q: 21. In each of the following cases of disputed paternity, identify the probable father: Blood type…

A: The paternity can be determined by taking probable genotypes and getting the parent genotypes…

Q: Writing/Response Prompt: Theorize about the following - Where do harmful genes that contribute to…

A: Each organism's DNA sequence is unique. Its base-pair sequence might vary from time to time. It is…

Q: Explain Nomenclature of neoplasia. provide examples

A: Neoplasia refers to the uncontrolled, abnormal growth of cells or tissues in the body; the abnormal…

Q: Explain the difference between mutation and DNA damage.

A: DNA is deoxyribonucleic acid. It is the genetic material and is responsible for carrying genetic…

Q: Explain the following statements in 4-6 lines each:   Premalignant (hyperplastic or dysplastic)…

A: Premalignant cells are also known as precancerous cells. These are the abnormal cells that have the…

Q: . For A and B, 1. Identify the type of inheritance. Justify your answer. 2. Decode the genotypes of…

A: Pedigree analysis is a diagrammatic representation of the inheritance of a particular trait…

Q: Explain the following term: Gene:

A: Genes are found on chromosomes, which are small spaghetti-like structures.

Q: Explain about several clinical stages that arecharacterized by the stepwise accumulation of genetic…

A: Genetic defects are changes in the DNA that can be passed down from generation to generation. These…

Q: Explain about dominant negative mutation ?

A: Mutation is any change in the DNA or RNA sequence which may or may not alter the normal functioning…

Q: Define: Gene Therapy:

A: Gene therapy is a technique which involves the insertion of the normal functional gene into the cell…

Q: Give the genetic cause (chromosomal abnormality and genes affected), and major characteristics of…

A: Genetic disorders  Disorders that are inherited from parents to their offsprings is know as genetic…

Q: Define common variants

A: A common variant is a part of a hypothesis "Common diseases-common variant" that accounts for the…

Q: Discuss types of DNA damage and how such lesions can be repaired.

A: Mutations arise not only from errors in replication but also through the damage in DNA. Some damage…

Q: For the P53 gene, briefly summarize relevant disease information and provide molecular diagnosis…

A: Carcinoma can kill when it infiltrates vital organs such as your liver, lungs, or brain and prevents…

Q: Duchenne muscular dystrophy describe the function of the gene and gene product as well as the…

A: Duchenne muscular dystrophy (DMD) is a genetic disorder, in which progressive muscle degeneration…

Q: List 3 causes of cancer:

A: Cancer Cancer is the uncontrolled growth of abnormal cells anywhere in a body- cancer cell. It is…