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Diltiazem is prescribed to treat hypertension, and simvastatin is a cholesterol-lowering drug. Locate the chirality centers in each. (CH3)2N НО. -OCCH3 H3C CH3 CH3 `OCH3 H3C Diltiazem Simvastatin

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter5: Stereochemistry At Tetrahedral Centers

Section5.SE: Something Extra

Problem 50AP

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Concept explainers

Stereochemistry and Isomerism

Stereochemistry deals with the three-dimensional structure and properties of molecules. It explains the arrangement of atoms and their manipulation within a molecule in a 3D structure. Stereochemistry can be dealt with all types of molecules. Based on the stereochemistry of a molecule, the physical and chemical properties of the molecules vary.

Question

4.31
Diltiazem is prescribed to treat hypertension, and simvastatin is a cholesterol-lowering drug. Locate the
chirality centers in each.
(CH3)2N
НО,
N-
||
-ОССH,
H;C CH3
CH3
ОСНЗ
H3C
Diltiazem
Simvastatin

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Chiral centre is the centre in which the carbon atom is surrounded by four different atoms.

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