Diazepam is used as a skeletal muscle relaxant and as a sedative administered before surgery, aswell as a treatment for anxiety. For children above the age of 6 months who suffer from anxietydisorders, diazepam is administered at a reduced dosage. Suppose a child with a body surface area(BSA) of 0.8 m2 is to receive a dose of diazepam divided into three administrations. Using the BSArule and assuming that an adult dose of diazepam is 12 mg, what are the daily dose and the doseper administration?mg

As a nurse its her responsibility to remember the formula while calculating the drug to avoid…

Answered: Diazepam is used as a skeletal muscle…

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

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A child who weighs 44 pounds receives a prescription for hydroxyzine.The recommended range for an intramuscularly dose in o.5 mg to 1mg/kg/dose. What is the maximum safe dose in milligrams that this child should receive
Explain the term first-pass eject or hepatic metabolism of the drug. What effect does first-pass have on drug bioavailability and activity?
a 4 YO 38lb child with hypertension has to be ordered furosemide 1mg/kg/dose PO twice daily. Furosemide oral solution is available in 60mL bottles containing 10mg/mL. How many mL will you administer each dose?
Two twins with identical physiology, biochemistry, weight and height are exposed to a total of 5 mg/day of chemically identical airborne particulate matter (PM), containing PAHs and heavy metals. This exposure occurs for 2 years. Twin A is predominantly exposed to PM10 while Twin B is predominantly exposed to PM2.5. Both twins will experience identical chronic toxicity because both had the same total dose - True of False. Please type answer note write by hend.
Calculate the following dosage: A doctor's prescription for pepcid is 15.5 mg per kg of body weight per dose. For an adult who weighs 135 lbs, calculate the number of grams to be given in a dose.
EPO injections, used as an ergogenic approach, are a risk to health, due to the significant increases in blood viscosity that can result, particularly after prolonged endurance exercise (e.g., a 5-hour bike ride). True False
1) A patient with heart failure, hypertension and hyperlipidemia is taking furosemide, captopril, atenolol, and simvastatin. During a scheduled physical examination, about a month after starting all the drugs, the patient reports a severe, hacking and relentless cough. Which of the following is the most likely cause of the cough? An expected effect of the captopril An allergic reaction to the statin Dyspnea due to captopril’s bronchoconstrictor action Hyperkalemia caused by an interaction between furosemide and captopril Excessive doses of furosemide, which lead to hypovolemia 2) Flecainide and propafenone are in Vaughan-Williams (antiarrhythmic) Class IC. What is the clinically relevant “take home” message about this class of drugs? Are only given for arrhythmias during acute myocardial infarction (MI) Are particularly suited for patients with low ejection fraction or cardiac output Are preferred drugs for relatively non-severe ventricular arrhythmias Have a significant…
Ideal weight of a child (Table 12.1) is 4.2 kg at 1 month, 5.6 kg at 3 months, 7.7 kg at 6 months, 10 kg at 1 year, 15 kg at 2 years, 18 kg at 5 years and 23 kg at 7 years. The paediatric dose of the opioid analgesic morphine in the APF is 0.1-0.2 mg/kg 2-4 hourly for subcutaneous administration (injection). A 5 year old child, who weighs 18.1 kg requires a 0.11 mg/kg dose of morphine. Calculate the volume of a 10 mg/mL solution that would be required / dose. (Answer to 2 significant figures.)
The initial plasma concentration of a drug given iv at 8:00am is 210 mg/ml. If the half life of the drug is 6 hours, what will the plasma concentration be at 7:00pm that same day?
4) A 45-year old woman weighing 68 kg is admitted to hospital after a drug overdose. A toxic plasma concentration of 264 mg/mL is recorded on admission. After 35 hours, a plasma concentration of 8.25mg/ml is recorded. Given this information, calculate the half life for this drug.(Assume the distribution is complete and that the elimination is described by a first-order process.)unit- hours
A 10-week-old child suffered from a salt-wasting crisis. His adrenal glands were enlarged and other organs were normal size. The child is phenotypically female, karotyping showed that the child is 46XY. The biochemical profile shows as: - sodium of 109 (reference range: 134-147) - potassium of 6.1 (reference range: 3.5-5.0) - pregnenlone of 0.002 (reference range: 0.3-1.5) - renin activity of 38 (reference range: 0.5-3.5) - 17-OH pregnenolone of 0.01 (reference range: 6.8-93.5) - ACTH of 1960 (reference range: 0.5-3.5) The cholesterol esters in the adrenal glands accumulated and the concentration of ∆4-androstenedione was not detectable. Also, the enzymes in the steroid biosynthesis did not have detrimental mutations. The child was given treatment with glucocorticoid and mineralocorticoid. Question: a) Which protein is deficient in this case and explain the rationale.
Write the drug drug interaction between Atenolol and Ponesimod ? Please shortly write at your own words. Answer should include the effects and mechanism.

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