1) A patient with heart failure, hypertension and hyperlipidemia is taking furosemide, captopril, atenolol, and simvastatin. During a scheduled physical examination, about a month after starting all the drugs, the patient reports a severe, hacking and relentless cough. Which of the following is the most likely cause of the cough?An expected effect of the captoprilAn allergic reaction to the statinDyspnea due to captopril’s bronchoconstrictor actionHyperkalemia caused by an interaction between furosemide and captoprilExcessive doses of furosemide, which lead to hypovolemia2) Flecainide and propafenone are in Vaughan-Williams (antiarrhythmic) Class IC. What is the clinically relevant “take home” message about this class of drugs?Are only given for arrhythmias during acute myocardial infarction (MI)Are particularly suited for patients with low ejection fraction or cardiac outputAre preferred drugs for relatively non-severe ventricular arrhythmiasHave a significant pro-arrhythmic effect (induction of lethal arrhythmias)Cause pulmonary fibrosis and a hypo-thyroid syndrome when given long term.

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Answered: 1) A patient with heart failure,…

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter9: Parenteral Medication Labels And Dosage Calculation

Section: Chapter Questions

Problem 7.7P

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1) A patient with heart failure, hypertension and hyperlipidemia is taking furosemide, captopril, atenolol, and simvastatin. During a scheduled physical examination, about a month after starting all the drugs, the patient reports a severe, hacking and relentless cough. Which of the following is the most likely cause of the cough?

An expected effect of the captopril
An allergic reaction to the statin
Dyspnea due to captopril’s bronchoconstrictor action
Hyperkalemia caused by an interaction between furosemide and captopril
Excessive doses of furosemide, which lead to hypovolemia

2) Flecainide and propafenone are in Vaughan-Williams (antiarrhythmic) Class IC. What is the clinically relevant “take home” message about this class of drugs?

Are only given for arrhythmias during acute myocardial infarction (MI)
Are particularly suited for patients with low ejection fraction or cardiac output
Are preferred drugs for relatively non-severe ventricular arrhythmias
Have a significant pro-arrhythmic effect (induction of lethal arrhythmias)
Cause pulmonary fibrosis and a hypo-thyroid syndrome when given long term.

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