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Define the following terms:
a. glutamate family
b. THF
c. AST
d. GOT
e. shikimate pathway
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Solved in 3 steps
- Define the following terms:a. alditolb. enediolc. epimerizationd. acetale. ketalDefine the following terms:a. adipocyteb. MCADc. ACPd. a-oxidatione. odd-chain oxidationDefine the following terms: a. respiratory control b. glycerol-3-phosphate shuttle c. uncoupling protein d. oligomycin e. malate–aspartate
- Alpha-glucosidase inhibitors are contraindicated in all of the following cases, except:A. Diabetic ketoacidosisA. Liver cirrhosisB. HypertensionC. Large abdominal herniasD. Ulcerative colitisDefine the following terms: a. thiolytic cleavage b. ketogenesis c. ketone bodies d. α-oxidation e. ACCDraw the structures of the major metabolites you would predict (Phase I and Phase II) for the non-steroidal anti-inflammatory drug naproxen and the beta blocker propranolol (use hand drawn illustrations or free chemistry drawing software, e.g. Marvin, for your answer). Explain how these metabolites are formed and comment on the role of metabolism (Phase I and Phase II) in the detoxification of the drugs.
- Define the following terms: a. ketogenic amino acid b. glucogenic amino acid c. L-amino acid oxidase d. Krebs urea cycle e. CPSIA patient who has been drinking large amounts of alcohol for long periods of time shows thefollowing symptoms: apathy, loss of memory, and a rhythmical to-and-fro motion of the eyeballs.Which of the following reactions are most likely to be affected in the patient? A. Conversation of pyruvate to acetyl-CoA B. Conversation of a-ketoglutarate to succinyl-CoA C. Both A and B D. Neither A nor BDefine the following terms:a. cytochrome P450b. mixed-function oxidasec. flavin-containing monooxygenased. detoxicatione. detoxification
- Define the following terms:a. b-oxidationb. carnitinec. ketogenesisd. ketone bodiese. ketosisWhich of the following enzyme components of fatty acid synthase has/have a thiol group? A. ketoacyl-ACP reductase B. ketoacyl-ACP synthase C. enoyl- ACP reductase D. acyl carrier proteinWhich of the following metabolite negatively regulates pyruvate kinase? Select one: a. Fructose-1,6-Bisphosphate b. Acetyl CoA C. Alanine d. Citrate