Define about the VNTR-Based DNA Fingerprinting ?

What impact has recombinant DNA technology had on genetics and society?

Suppose you are arrested for a serious crime and a DNA profile is created and entered into databases. Later, you are proven innocent. Should you have the right to have your DNA profile removed from all databases?

Do you think the way this issue was handled should be a model for future situations involving potential dangers that might arise from research methods or results?

What is the most challenging issue facing genome sequencing? a. the inability to develop fast and accurate sequencing techniques b. the ethics of using information from genomes at the individual level c. the availability and stability of DNA d. all of the above

Which of the following is NOT an activity carried out in the field of bioinformatics? a. collecting and storing DNA sequence information produced by various genome sequencing projects b. analyzing genome sequences to determine the location of genes c. determining the three-dimensional structure of proteins d. comparing genomes of different species e. none of these

Gene therapy involves: a. the introduction of recombinant proteins into individuals b. cloning human genes into plants c. the introduction of a normal gene into an individual carrying a mutant copy d. DNA fingerprinting e. none of these

What additional biological questions can be answered if one has the complete sequence of an organisms genome as compared with the sequences of individual genes?

Can DNA profiling identify the source of a sample with absolute certainty? Because any two human genomes differ at about 3 million sites, no two persons (except identical twins) have the same DNA sequence. Unique identification with DNA profiling is therefore possible if enough sites of variation are examined. However, the systems used today examine only a few sites of variation. Nonetheless, even with todays technology, which uses three to five loci, a match between two DNA patterns can be considered strong evidence that the two samples came from the same source. DNA profiling in criminal cases has been a useful tool in establishing both guilt and innocence. Originally, DNA databases contained only the profiles of convicted felons. Over time, however, law enforcement agencies have expanded the collection and use of DNA profiles, and these new policies are causing controversies, once again illustrating how the availability and use of genetic technology is often ahead of consensus on how and when this technology should be used. One of these new policies is postarrest DNA collection. At this writing, 18 U.S. states as well as the federal government allow the collection of DNA samples after an arrest but before conviction. These profiles become part of the states DNA database, which is often searched for evidence in cold cases. Courts across the country have ruled for and against the use of such samples. In 2012, the Maryland Court of Appeals ruled that the collection of DNA samples from someone who has been arrested but not convicted is unconstitutional and violates an individuals right to be free from unreasonable search and seizure. The case began when a DNA sample was taken from Alonzo Jay King, Jr., who was arrested in 2009 for assault. In a database search, the DNA profile matched that taken from a 2003 unsolved rape. Based on the results of the database search, the man was sentenced to life in prison. The rape conviction was reversed, and the case was sent back to a lower court. As a result, some 16,000 DNA profiles collected postarrest but preconviction since 2009 cannot be used pending appeal of this decision. Before the court decision, postarrest DNA profiles were used in 65 arrests that resulted in 34 convictions, with an additional 12 cases pending. Supporters of postarrest DNA profiling claim that taking a DNA sample by a cheek swab is noninvasive and no different from taking someones fingerprints. Opponents claim that because DNA samples can be used to determine much more than a DNA profile, they are a threat to privacy, and that because minorities are more likely to be arrested, the practice is discriminatory. What are your thoughts on the collection and use of postarrest DNA profiles?

Can DNA profiling identify the source of a sample with absolute certainty? Because any two human genomes differ at about 3 million sites, no two persons (except identical twins) have the same DNA sequence. Unique identification with DNA profiling is therefore possible if enough sites of variation are examined. However, the systems used today examine only a few sites of variation. Nonetheless, even with todays technology, which uses three to five loci, a match between two DNA patterns can be considered strong evidence that the two samples came from the same source. DNA profiling in criminal cases has been a useful tool in establishing both guilt and innocence. Originally, DNA databases contained only the profiles of convicted felons. Over time, however, law enforcement agencies have expanded the collection and use of DNA profiles, and these new policies are causing controversies, once again illustrating how the availability and use of genetic technology is often ahead of consensus on how and when this technology should be used. One of these new policies is postarrest DNA collection. At this writing, 18 U.S. states as well as the federal government allow the collection of DNA samples after an arrest but before conviction. These profiles become part of the states DNA database, which is often searched for evidence in cold cases. Courts across the country have ruled for and against the use of such samples. In 2012, the Maryland Court of Appeals ruled that the collection of DNA samples from someone who has been arrested but not convicted is unconstitutional and violates an individuals right to be free from unreasonable search and seizure. The case began when a DNA sample was taken from Alonzo Jay King, Jr., who was arrested in 2009 for assault. In a database search, the DNA profile matched that taken from a 2003 unsolved rape. Based on the results of the database search, the man was sentenced to life in prison. The rape conviction was reversed, and the case was sent back to a lower court. As a result, some 16,000 DNA profiles collected postarrest but preconviction since 2009 cannot be used pending appeal of this decision. Before the court decision, postarrest DNA profiles were used in 65 arrests that resulted in 34 convictions, with an additional 12 cases pending. Supporters of postarrest DNA profiling claim that taking a DNA sample by a cheek swab is noninvasive and no different from taking someones fingerprints. Opponents claim that because DNA samples can be used to determine much more than a DNA profile, they are a threat to privacy, and that because minorities are more likely to be arrested, the practice is discriminatory. Would you object if you were arrested for a minor offense, such as a traffic violation, and ordered to provide a DNA sample?