d. .CO₂K 1. 12, CH3CN, -15 °C 2. BnOK, THF, -20 °C D

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Chapter1: Chemical Foundations
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problem d please

Stereochemistry. Give the structure and predict the stereochemistry of the major
product formed in each of the following reactions. Give an explanation for your
choice of stereochemistry.
a.
b.
C.
d.
Me
t-Bu
HO
Me
OH
Me
Me
1. Ti(Oi-Pr)4, (+)-DET
TBHP, CH₂Cl₂
2. H₂C=CHCH₂MgCl
THF
CO₂K
OBPS
a. BH3, THF
b. NaOH, H₂O2
OBn
1. Ti(O+-Pr)4
B
(-)-DET, t-BuOOH
CH₂Cl2, -20 °C
2. Red-AI, THF, rt
A1
1. 12, CH3CN, -15 °C
2. BnOK, THF, -20 °C
►D
3. (MeO)2CMe2
cat. H+
4a. O3, EtOH, -78 °C
4b. Me₂S, NaBH4
с
A2
Transcribed Image Text:Stereochemistry. Give the structure and predict the stereochemistry of the major product formed in each of the following reactions. Give an explanation for your choice of stereochemistry. a. b. C. d. Me t-Bu HO Me OH Me Me 1. Ti(Oi-Pr)4, (+)-DET TBHP, CH₂Cl₂ 2. H₂C=CHCH₂MgCl THF CO₂K OBPS a. BH3, THF b. NaOH, H₂O2 OBn 1. Ti(O+-Pr)4 B (-)-DET, t-BuOOH CH₂Cl2, -20 °C 2. Red-AI, THF, rt A1 1. 12, CH3CN, -15 °C 2. BnOK, THF, -20 °C ►D 3. (MeO)2CMe2 cat. H+ 4a. O3, EtOH, -78 °C 4b. Me₂S, NaBH4 с A2
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