Cystic fibrosis is genetic disease caused by mutations in the CFTR gene. The consequence of this is production of an abnormal transmembrane protein that is responsible for producing sweat, mucus, and digestive fluids. Explain in depth the correlation between the defective gene and the abnormal protein that is produced.

Q: The maximum number of amino acids that coded by 40 nucleotides in the MRNA are

A: mRNA plays a specific role in protein synthesis in the cell.

Q: • Transposable elements are short segments of DNA, presentin multiple locations, that move around…

A: Genes are the basic structural and functional unit of heredity. They carry coded genetic information…

Q: Aminoacyl-tRNA synthetases are the only component of gene expression that decodes the genetic code.…

A: The protein synthesis involves the synthesis of the polypeptide chain which is catalyzed by several…

Q: Define . Nonsense codon  as they apply to the genetic code

A: Codons are the triplet of nucleotides present in DNA (deoxyribonucleic acid) or RNA (ribonucleic…

Q: Cystic fibrosis is a genetic disease caused by mutations in the CFTR gene. The consequence of this…

A: Cystic fibrosis is a genetic disease majorly affecting lungs alongside the pancreas, liver,…

Q: If the DNA duplex for the beta chain of haemoglobin 3'-TACCACGTGGACTGAGGACTCCTCTTCAGA-5' were…

A: Answer: TRANSCRIPTION = It is process of transcribing a strand of DNA using RNA polymerase which…

Q: is the various steps of protein production in eukaryotic cells and their localization (from a gene…

A: Protein is a very important part of the cell because it it is the ultimate machinery through which…

Q: occur as a result of biotransformation

A: The process of chemically changing the compounds inside the body from one compound to a different…

Q: Cystic Fibrosis is a genetically heritable disease caused by the loss of the chloride channel, CFTR.…

A: Cystic fibrosis is a genetic disease that is characterized by the production of excessively thick…

Q: Determine the reason due to which it is possible that the translation of a single mitochondrial…

A: Given that tRNAs are impacted by numerous clinical mitochondrial illnesses brought on by mutations…

Q: Write a possible sequence for an mRNA segment coding for apamine

A: Introduction  Genome is referred to the total amount of DNA a single haploid cell contains. Genome…

Q: what are exceptions found in mitochondria to theuniversal genetic code.?ac

A: The DNA is the genetic material that is passed from one generation to the next generation. It is…

Q: Explain why a loss or an excess in genetic material leads to the expression of an abnormal

A: Introduction :- Mutations are changes in a gene's DNA that are abnormal. Bases are the basic…

Q: Mutations that introduce stop codons cause a number of genetic diseases. For example, from 2% to 5%…

A: Non-sense mediated mRNA decay (NMD) is a technique evolved by the eukaryotic cells to prevent the…

Q: Some transcription factors contain bromodomains. Explain the function of the bromodomain?

A: Transcription factors are responsible for intiating the transcription process. The transcript…

Q: Discuss the following statement: “from the nucleotide sequence of a cDNA clone, the complete amino…

A: The proteins are the polymer of amino acids. They play an important role in the cell, by catalyzing…

Q: Mutations that introduce stop codons cause a number of genetic diseases. For example, from 2% to 5%…

A: Non-sense mediated mRNA decay (NMD) is a technique evolved by the eukaryotic cells to prevent the…

Q: In many genetic disorders, a lysosomal enzyme required to degrade a specific molecule is missing or…

A: Tay–Sachs disease is an inherited disorder that causes the destruction of neurons in the spinal cord…

Q: Suppose the DNA sequence of a gene with 5 exons contains a mutation at the 5’ end of intron 2.…

A: The protein translation is the process of the formation of proteins from the mRNA formed from the…

Q: The bli-1 gene in C.elegans is a type of    tubulin  actin integrin collagen

A: Gene  Gene is a set of nucleotide sequence present in the DNA which code for specific polypeptide…

Q: What is known as zip code binding protein 1 (ZBP1) ?

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Q: The steps required for peptide elongation at the ribosome are, respectively, (A) initiation,…

A: The step of the protein biosynthetic pathway involved in the development of nascent polypeptide…

Q: Select any of the choices that would be considered a post-transcriptional modification of…

A: Since you have posted multiple question, we will solve the first question for you. If you want any…

Q: The peptide hormone glucagon tends to elevated in between meals. Among the effects that glucagon has…

A: Eukaryotic elongation Factor 2 (eEF2) mediates translocation of peptidyl-tRNA from A-site to P site…

Q: A significant number of mutations in the HBB gene that causehuman β thalassemia occur within introns…

A: A mutation occurs when the sequence of DNA changes. Mutations can occur as a result of DNA copying…

Q: Define the following terms: a. proteasome b. ubiquitination c. ubiquitin-conjugating system d.…

A: Molecular biology is the branch of science that deals with different molecules inside the body which…

Q: An integral membrane protein has an ER signal sequence near its N terminus and a stop transfer…

A: Transcription: It is processed to convert DNA into RNA. It is part of the central dogma. It is…

Q: Name four types of point mutations that can occur in a gene coding for a protein. Discuss the…

A: The DNA (deoxyribonucleic acid) is the double-stranded molecule that is the genetic material in most…

Q: The tumor suppressor pRB also binds to and suppresses the activity of retinoblastoma-binding protein…

A: Mutation in genes is the process of change in the nucleotide sequence of the genome.

Q: Like Hurler syndrome, Fabry disease involves an abnormal accumulationof substances within lysosomes.…

A: Gene is a functional unit of heredity. A gene is a sequence of nucleotides in genome that codes for…

Q: describe the process of lysosomal hydrolase arriving to the lysosome. without including translation

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Q: You are investigating a lysosomal storage disease and you discover that newly synthesized lysosome…

A: When normally a protein is destined to be targeted to lysosome, then the proteins are modified in…

Q: the synthesis of mRNA from

A: outside (cytoplasm).-In DNA, uses nucleotide sequence to prepare the mRNA "blueprints." The mRNA…

Q: Consider the example that actin mRNA localization is important for fibroblast migration. What would…

A: it is required for cell proliferation.

Q: What is the net gain in the number of chemical bonds during splicing of an intron? Please explain…

A: During the splicing of interon 2 phosphodister bonds are broken                  But 2 bonds are are…

Q: TRUE OR FALSE Errors in transcription can lead to silent mutations encoding the same amino acid or…

A: Silent mutations are the type of mutations in which base substitution has no effect in…

Q: Human histone H1 protein has the protein sequence as shown as “KKASKPKKAAS-…

A: Histone H1 protein K in the sequence represents lysine The given histone sequence is rich in lysine…

Q: Which regulatory proteins binds to specific DNA sequences with high affinity and plays a…

A: Regulatory proteins are a family of specialized proteins that play a major role in the transcription…

Q: A human gene called theCFTR gene (for cystic fibrosis transmembrane regulator) encodes aprotein that…

A: A disease is an abnormal condition that negatively impacts the structure and function of an…

Q: Hurler syndrome is due to a mutation in a gene that encodes aprotein called α-l-iduronidase. This…

A: Hurler syndrome is an autosomal recessive disorder and the affected person carries two…

Q: Cystic fibrosis is genetic disease caused by mutations in the CFTR gene. The consequence of this is…

A: Cystic fibrosis is a rare genetic disorder that occurs when there is an inherited mutation in cystic…

Q: The post-translational modification called collagen (one word = noun) is essential in the…

A: In living organisms, all the physiological and biochemical actions are performed by the appropriate…

Q: Cystic fibrosis is genetic disease caused by mutations in the CFTR gene. The consequence of this is…

A:

Q: Familial hypercholesterolemia is a genetic condition characterized by an absence of functional LDL…

A: About 1 in 100 to 200 people have mutations in the LDLR gene that encodes the LDL receptor protein,…

Q: The tumor suppressor pRB also binds to and suppresses theactivity of retinoblastoma binding protein…

A: The segments of the genetic material which helps in the expression of the characters are known as…

Q: Please choose the correct answer. If nutritional requirements are not met, gene expression will most…

A: Introduction Gene expression is the process through which information from a gene is utilised in the…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.