Current Attempt in Progress Synthetic chemists often employ enzymes to conduct asymmetric syntheses that favor the production of one enantiomer over another. Baker's yeast was used to convert the diketone shown into alcohol 1, with an ee of 84%. (Tetrahedron Asymmetry 2014, 25. 340-347.) The specific rotation for the pure (S) enantiomer of 1 is reported to be +88.6. Calculate the expected specific rotation for the sample of 1 that was synthesized with baker's yeast. OMe MeO Touthook and Media Baker's yeast MeO OH Compound 1 OMe

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Synthetic chemists often employ enzymes to conduct asymmetric syntheses that favor the production of one enantiomer over
another. Baker's yeast was used to convert the diketone shown into alcohol 1, with an ee of 84%. (Tetrahedron Asymmetry 2014, 25.
340-347.) The specific rotation for the pure (S) enantiomer of 1 is reported to be +88.6. Calculate the expected specific rotation for
the sample of 1 that was synthesized with baker's yeast.
OMe
MeO
Touthook and Media
Baker's yeast
MeO
OH
Compound 1
OMe
Transcribed Image Text:Current Attempt in Progress Synthetic chemists often employ enzymes to conduct asymmetric syntheses that favor the production of one enantiomer over another. Baker's yeast was used to convert the diketone shown into alcohol 1, with an ee of 84%. (Tetrahedron Asymmetry 2014, 25. 340-347.) The specific rotation for the pure (S) enantiomer of 1 is reported to be +88.6. Calculate the expected specific rotation for the sample of 1 that was synthesized with baker's yeast. OMe MeO Touthook and Media Baker's yeast MeO OH Compound 1 OMe
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