Cotranscriptional processing of RNA (a) Capping Transcription start site Cap CTD Capping enzymes (b) Splicing CTD RNA splicing 5 machinery (c) Cleavage and polyadenylation Poly(A) tail added (d) Final product - Poly(A) tail FIGURE 8-13 Cotranscriptional processing of RNA is coordinated by the carboxyl tal domain (CTD) of the B subunit of RNA polymerase II Reversible phosphorylation of the amino acids of the CTD (indicated by the P's) creates binding sites for the different processing enzymes and factors required for (a) capping, (b) splicing, and (c) cleavage and polyadenylation.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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How do you know that the events in Figure 8-13 are occurring in the nucleus?

Cotranscriptional processing of RNA
(a) Capping
Transcription
start site
Cap
CTD
Capping
enzymes
(b) Splicing
CTD
RNA splicing 5
machinery
(c) Cleavage and polyadenylation
Poly(A) tail added
(d) Final product
- Poly(A) tail
FIGURE 8-13 Cotranscriptional processing of RNA is coordinated by
the carboxyl tal domain (CTD) of the B subunit of RNA polymerase II
Reversible phosphorylation of the amino acids of the CTD (indicated
by the P's) creates binding sites for the different processing enzymes
and factors required for (a) capping, (b) splicing, and (c) cleavage and
polyadenylation.
Transcribed Image Text:Cotranscriptional processing of RNA (a) Capping Transcription start site Cap CTD Capping enzymes (b) Splicing CTD RNA splicing 5 machinery (c) Cleavage and polyadenylation Poly(A) tail added (d) Final product - Poly(A) tail FIGURE 8-13 Cotranscriptional processing of RNA is coordinated by the carboxyl tal domain (CTD) of the B subunit of RNA polymerase II Reversible phosphorylation of the amino acids of the CTD (indicated by the P's) creates binding sites for the different processing enzymes and factors required for (a) capping, (b) splicing, and (c) cleavage and polyadenylation.
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