CO0- | CH, CO0- CO2 CH, CH2 CH, C=0 C=0 CO0- H a-Ketoglutarate Succinate semialdehyde

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
icon
Concept explainers
Question

Certain microorganisms with a modified citric acid cycle decarboxylate a-ketoglutarate to produce succinate semialdehyde:

(a) Succinate semialdehyde is then converted to succinate, which is further
metabolized by standard citric acid cycle enzymes. What kind of reaction
is required to convert succinate semialdehyde to succinate? Show
any coenzymes that might be involved.
(b) Based on your answer in part a, how does this pathway compare to the
standard citric acid cycle in energy yield?

CO0-
|
CH,
CO0-
CO2
CH,
CH2
CH,
C=0
C=0
CO0-
H
a-Ketoglutarate
Succinate semialdehyde
Transcribed Image Text:CO0- | CH, CO0- CO2 CH, CH2 CH, C=0 C=0 CO0- H a-Ketoglutarate Succinate semialdehyde
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 4 steps

Blurred answer
Knowledge Booster
Metabolic pathways
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON