Consider the reaction of 2-bromo-2-methylpropane with water, shown below, to answer the following question(s). CH3 H₂C-C-Br I CH3 H₂O H₂C-C+ CH₂ CH3 H H₂C-C CH3 Diagram 1: The first step of this reaction is shown below. CH3 CH3 H₂C-C-Br H₂C-C+ CH3 H -OH CH3 B Diagram 2: The second and third steps of the reaction are shown below. CH3 CH₂ + CH₂ HC-C-64 CH₂ H + H Br HBr ÖH₂ H₂C- CH3 H + H₂O* 4) In Diagram 2, label the nucleophile, Nu, and the electrophile, E+, in the blanks provided under the structures.

Organic Chemistry
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ISBN:9781305080485
Author:John E. McMurry
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Chapter21: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions
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Problem 54AP: The following reactivity order has been found for the saponification of alkyl acetates by aqueous...
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Consider the reaction of 2-bromo-2-methylpropane with water, shown below, to answer the following
question(s).
CH;
H₂C-C- Br
CH3
H₂C-C-OH +
CH3
Diagram 1: The first step of this reaction is shown below.
CH₂
CH3
H₂C-C-Br
CH3
CH₂
H₂C-
CH₂
H₂O
:0
CH3
B
Diagram 2: The second and third steps of the reaction are shown below.
CH₂
H
H₂C C+
H
HC-
H
Br
CH₂ H
HBr
CH₂
¡ÖH₂ → H₂C—C—01
CH₂
H
+ H₂O*
4) In Diagram 2, label the nucleophile, Nu, and the electrophile, E+, in the blanks provided
under the structures.
Transcribed Image Text:Consider the reaction of 2-bromo-2-methylpropane with water, shown below, to answer the following question(s). CH; H₂C-C- Br CH3 H₂C-C-OH + CH3 Diagram 1: The first step of this reaction is shown below. CH₂ CH3 H₂C-C-Br CH3 CH₂ H₂C- CH₂ H₂O :0 CH3 B Diagram 2: The second and third steps of the reaction are shown below. CH₂ H H₂C C+ H HC- H Br CH₂ H HBr CH₂ ¡ÖH₂ → H₂C—C—01 CH₂ H + H₂O* 4) In Diagram 2, label the nucleophile, Nu, and the electrophile, E+, in the blanks provided under the structures.
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John E. McMurry
Publisher:
Cengage Learning