Consider the equilibrium of arginine below: NH₂ NH₂ H₂N: 0 NH OH H₂NE pKa-2.17 NH3 NH H₂N: pKa 9.04 NH3 NH₂ NH .00 HN: pKas 12.48 NH₂ I II III If the pH of arginine solution is 8.08, what would be the major form of arginine? NH₂ NH 00 -NH₂ IV
Q: Which of the following statements about the TCA cycle is INCORRECT? O a. The TCA cycle can recover…
A: An inventive set of eight reactions makes up the TCA cycle. It is a crucial route that uses a…
Q: What is true about lipids? A. They are polar and therefore soluble in polar solvents B They are…
A: The four classes of biological macromolecules are nucleic acids, proteins, lipids and…
Q: The citric acid cycle is shown. The methyl carbon in acetyl CoA is labeled with C14C14 (shown in…
A: Carbon tracing is a biochemical technique of tracking the path taken by a specific carbon atom in a…
Q: Based solely on the amount of NADPH produced, what is the total number of photons of light that must…
A: In the photosystems, NADPH is produced by a series of reactions starting from absorption of photons.…
Q: Discuss the cellular location and biological significance of the processes of the citric acid cycle…
A: Cellular respiration is a collection of three metabolic pathways that generate ATP by the oxidation…
Q: Draw the synthesis of the dinucleotide formed between ATP and GMP. The 5' triphosphate can be…
A: Guanosine Monophosphate kinase catalyze the phosphate transfer reaction in which the terminal gamma…
Q: draw a guanine nucleobase and label all possible H bond donor and H bond acceptor?
A: H bond donor are those groups containing a H bonded to a electronegative atom (F,O,N) and H bond…
Q: Which of the following statements is true about the well-fed state? O a. Liver glycogen is…
A: The well-fed state is the absorptive state that begins immediately after meal consumption. It is…
Q: Given the Fischer projection structure of D-Lasallose below, show the step by step process of…
A: Given to us is a 7 carbon ketose sugar. We can number the carbon atoms as shown below. figure 1 The…
Q: *Give an example, taken from digestion, glycolysis, gluconeogenesis or the citric acid cycle of each…
A: Let us first understand the following terms: Feedback inhibition: It is a type of regulation or…
Q: What are the precipitates that were produced during the calcium and chloride ion test when it comes…
A: When it comes to analysis of blood, the calcium ions are determined by addition of oxalate ions that…
Q: Several hours after a meal, the brain uses [Select] [Select] During starvation, the brain uses…
A: Carbohydrates are one of the three primary nutrients included in foods and beverages, along with…
Q: Show the structure of each intermediate in the conversion of b-hydroxybutyryl-ACP to butyryl-ACP by…
A: De novo fatty acid synthesis is also called as Lynen's spiral is a set of reactions catalysed by a…
Q: 16. The overall reaction for the glycolysis reaction is C6H₁2O6(aq) + 2NAD+ (aq) + 2ADP³- (aq) +…
A: Glycolysis is the breakdown (catabolism) of glucose into pyruvate with net generation of 2ATP and…
Q: Describe how the activity and specificity of ribonucleotide reductase (RNR) is regulated.
A: Ribonucleotide reductase (RNR) catalyzes the rate-limiting step in the only known de novo pathway…
Q: Two villages in the Amazon depend on corn as a major staple in their diet. People in village A have…
A: Pellagra is a deficiency disease which is characterised by diarrhoea, mental disturbance, scaly…
Q: DNA polymerase I functions in DNA replication to: O a. O b. O C. synthesize the RNA primer…
A: The replication process is in which there is synthesis of DNA using DNA strand. There are various…
Q: Carnitine combines with fatty acids groups to form acyl carnitine through carnitines ____ group…
A: Beta-oxidation of fatty acids occurs in mitochondria. Before beta-oxidation starts each fatty acids…
Q: all of the following statements about mitochondrial oxidative phosphorylation are true EXCEPT a. The…
A: The metabolic pathway in which cells use enzymes to oxidize nutrients, releasing chemical energy and…
Q: why the Shine–Dalgarno sequence is important to prokaryotes?State the bases of prokayotes’ mRNA
A: As per the central dogma of molecular biology, genetic information is stored in the DNA. The genetic…
Q: Why is it critical that NAD* and FAD be regenerated inside the mitochondrial matrix rather than the…
A: NAD+ and FAD are coenzymes derived from vitamin B3 and vitamin B2 respectively. Both NAD+ and FAD…
Q: You are studying a metabolic pathway and are trying to decide if it is an anabolic pathway or a…
A: Catabolic pathways are those that can breakdown the larger compounds into simple molecules. Anabolic…
Q: Which of the following liver metabolic pathways are not normally active at the same time but are…
A: Cortisol : This is steroid hormone that increases blood glucose levels. it decreases glucose uptake…
Q: Why is the name the "citrate cycle" a more accurate name for the metabolic pathway discovered by…
A: Critic acid cycle also called as tricarboxylic acid cycle is the second stage in aerobic cellular…
Q: true or false: The nitrogen atoms in purine rings come from glutamine.
A: Purine and pyrimidine are the two bases involved in formation of nucleotides.
Q: In order to activate glucose for storage as glycogen, what must be added to each glucose? A)…
A: Glycogen is a branched glucose polymer that is used as an energy reserve in animal cells. The…
Q: In extracellular proteins the amino acid Cys can interact with another Cys to form a bond sometimes…
A: Proteins are composed of amino acids, which are bound together by peptide linkage. Amino acids…
Q: Studies of the inner mitochondrial membrane reveal its composition to be approximately 20% lipid…
A: ATP is the energy currency that the cell spends on metabolic transactions. Mitochondria is the site…
Q: Please type out answer and need 200 word or more response Propose a reason for why so many of the…
A: Amino acids are biomolecules that have an amino group and a carboxyl group linked to the same carbon…
Q: Purine synthesis begins with the synthesis of IMP. Beginning with IMP, write the step(s) involved in…
A: Purines provide the essential components for DNA and RNA . They act as building blocks for the…
Q: The following compound is best identified as (blank). O *NH3-CH-C-NH-CH-COO- Ť" CH3 CH₂ OH O a…
A: Any living cell is made up of biomolecules. These biomolecules can be classified into the following…
Q: what is the net reaction of the citric acid cycle for a single acetyl coenzyme A molecule? what are…
A: TCA cycle is also called as Krebs cycle a cyclic process that converts Pyruvate to CO2. It is a…
Q: Phosphatidate is: O A) a precursor to triacylglycerol synthesis. O B) a phospholipid. OC) indirectly…
A: Phosphatidates are ester phospholipids and belong to the category of phospholipids. Their structure…
Q: true or false: A high dTTP concentration shifts the specificity of ribonucleotide reductase…
A: Ribonuclotide reductase is the enzyme that catalyses the conversion of NTPs to dNTPs. Ribonuclotide…
Q: Consider a situation where a mitochondrion contained a defective complex III that resulted in only…
A: Electron transport chain consists of a series of protein arranged in mitochondria membrane and…
Q: The lac operon contains three genes: lacZ, lacY, and lacA for ß-galactosidase, galactoside permease,…
A: Lac operon is a model of gene regulation system in prokaryotes. it consists of three genes , lac Z,…
Q: The Krebs cycle reaction shown below is catalyzed by __ enzyme and ___ pays for this reaction note…
A: The TCA cycle or Kreb cycle occurs in the mitochondrial matrix. The TCA cycle uses the acetate in…
Q: a. In active muscle cells, the pO2 is about 10 torr at the cell surface and 1 torr at the…
A: Myoglobin and hemoglobin are oxygen storage and transport proteins. Myoglobin, whose primary…
Q: Considering that regulation most often occurs at irreversible steps in a biochemical pathway, which…
A: Enzymes are usually protein molecules which catalyze several biochemical reactions in our body…
Q: Which of the following statements is true about the quaternary structure of protein? A) The…
A: There are 4 different types of proteins structures: 1. primary: It is the sequence of amino acids…
Q: *Determine the ATP yield from the metabolism of one molecule of glucose under the following…
A: Cellular respiration is a collection of three metabolic pathways that generate ATP by the oxidation…
Q: Identify the major and minor grooves in the DNA molecule PDB ID 141D. In addition, one end of a…
A: DNA is two strands of polynucleotide linked to each other in an antiparallel direction by hydrogen…
Q: The catalytic activity of enzymes depends on the presence of appropriate environmental conditions.…
A: Pepsin is a digestive enzyme found in the stomach. It is a type of hydrolase enzyme that help in…
Q: How many comparisons are needed to count the number of duplicates in a list? How many comparisons…
A: Codons are triplets of nucleotides (4 types of nucleotides, A, U, G, C) found on mRNA sequence which…
Q: Of the hydrolyzable lipids, which contain ester functional groups? A. Waxes B. Triacylglycerides C.…
A: Lipids are a very important class of biological molecule. Lipids are a broader class of molecule…
Q: An aminoacyl-tRNA is initially bound to the ribosome in prokaryote at the A site on the 70S subunit…
A: A small RNA molecule known as transfer RNA (tRNA) is essential for the production of proteins.…
Q: Consider the image of protein synthesis (translation). Identify the two different RNA molecules…
A: Translation refers to the process of protein synthesis. It falls under the process of gene…
Q: true or false: Guanylate phosphorylase is responsible for converting guanosine monophosphate into…
A: Nucleosides are pentose sugar linked to heterocyclic nitrogenous bases. Nucleotides are phosphoric…
Q: The following are effects. role of glycosylation, EXCEPT molecular recognition in immunologic…
A: Since you have posted multiple questions we will answer the first question for you. Please repost…
Q: Describe the role of each of the membrane proteins shown in the picture below. Think about what is…
A: The NADH and FADH2 formed during the glycolysis and TCA cycle transfer electrons to the oxygen. The…
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 1 images
- You are given 0.5 M solution of the amino acid Arginine. pK1 (α-carboxyl group) = 2.17 pK2 (α- amino group) = 9.03 and pK3 (guanidine group) = 12.48 Determine the pH of the solution if you add 15 mL 0.25 M HCl to 10 mL of the 0.5 M Arginine. Assume that Arginine is in isotonic state. Show all calculationsYou are given 0.5 M solution of the amino acid Arginine. pK1 (α-carboxyl group) = 2.17 pK2 (α- amino group) = 9.03 and pK3 (guanidine group) = 12.48 Determine the pH of the solution if you add 15 mL 0.25 M HCl to 10 mL of the 0.5 M Arginine. Assume that Arginine is in isotonic state. Show all calculations b. Draw the structure of the amino acid at the pH determined in question 1The amino acid arginine ionizes according to the following scheme: NH₂ I C=N I ΝΗ Part A pl = Submit H (CH₂)3 H-N-C-COOH II HH 1 [ΠΙ ΑΣΦ H H Calculate the isoelectric point of arginine. Express your answer using three significant figures. Request Answer pk-2.17 -H* +H* wwwww NH₂ C=N ΝΗ H (CH₂)3 1 ? H H-N-C-COO- | | H H 11 H pk-8.99 -H* +H* NH₂ I C=N I ΝΗ T (CH₂)3 H H H₂N-C-COO- I H pk - 12.5 -H* +H* NH₂ C=N=H NH I (CH₂)3 H₂N-C-COO- I H IV
- A 100 ml solution of 0.1 M amino acid (AA) at ph 1.0 was titrated with NaOH solution. The pH was monitored, and the results were plotted on the graph. The keypoints in the titration are designated I to VII. What is the possible identity of the amino acid? What is the isoelectric point of AA? what is the pKa corresponding to the dissociation of the alpha carboxylic group? Region/point where AA is predominantly present as a (-1) charged species? The effective buffering range for the amino acid in the acidic region? Region/point where the solution has 50:50 percent mixture of the (0) and (-1) speciesConcanavalin (ConA) is a 25.5KDa protein with pl of 4.7 and optical absorbance (A 0.1% 289) of 1.14. calculate the concentration of an aqueous solution of pure BSA protein with an absorbance of 0.66 at 280nm. give your answer in units of mg/ml ?Refer to the following titration curve below: 13 12 11 10 9 7 6 5 4 3 4 6 8 10 12 14 16 18 20 22 24 26 28 30 Volume of Titrant / mL - Unknown Acid 0.10 mol/L - titrant = NaOH 0.1 mol/L At ph 10.0, which form of histidine is most abundant? His2+ His- His° His+
- Draw the structural form of valine that predominates in solution at each of the following ph values: a. ph<pi ; b. pl ; c. ph>pi pk values: pk 1=2.2 ; pk2 = 9.7 Do also for asp (1.88, 9.60, 3.65) and lys (2.88, 8.95, 10.53)Draw the titration curve for an 800 mL 0.25 M solution of Arginine. (Graph pH vs. mole OH-.) Where onthe curve is the charge on Arginine +1.5? Identify it on the graph.A mixture of proteins contains four different polypeptides, all in ~equal concentration, in solution with the following properties: Protein Molecular Mass (kDa) Isoelectric point A 45 4.5 B 77 6.0 C 28 4.1 D 14 10.7 A fraction of the protein solution is applied to a strong cation exchange column using a buffer at pH 8.0 with increasing [NaCl] from 0.05 M – 1.0 M. The chromatogram is shown below: 1. Based on the data presented, which of the following statements is true: Peak #1 is protein D Peak #4 is protein C Peak #3 is protein A Peak #4 is protein D Peak #2 is protein B 2. Since you know that the proteins are all present in approximately equal concentrations, the different relative peak areas tell you that: There are more neutral amino acids in protein #4…
- The ionization of p-nitrophenol is shown below (pKa = 7.0): a. Identify the weak acid and conjugate base. b. At pH 7, what are the relative concentrations of ionized and un-ionized p-nitrophenol? c. If enough concentrated hydrochloric acid is added to a solution of p-nitrophenol to lower the pH from 7 to 5, what will happen to the relative concentrations of the ionized and un-ionized forms? d. Ionized p-nitrophenol has a yellow color, while the un-ionized form is colorless. The yellow color can be measured using a spectrophotometer at 400nm. In order to determine the total amount of p-nitrophenol in a solution, would you perform the spectrophotometer reading at an acidic or basic pH? Clearly explain why? e. A solution of p-nitrophenol at pH 7.95 was found to have an A400 of 0.255 . What is the total concentration (in µM) of p-nitrophenol (ionized plus un-ionized) in the solution? The molar extinction coefficient of p-nitrophenol is 18,500 M-1cm-1 and the pKa is 7.2. 0.1 mL of a protein solution of concentration of 7 mg/mL was diluted to a total volume of 4.0 mL with water (i.e. 0.1 mL of the solution was added to 3.9 mL of water). 3 mL of this solution was then mixed with 27 mL of water. What is the concentration of the diluted protein solution? Space to show your workings:The amino acid histidine has ionizable groups with p?a values of 1.8, 6.0, and 9.2, as shown. A biochemist makes up 95 mL of a 0.15 M solution of histidine at a pH of 5.3. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution?