Consider a study designed to estimate the role that certain characteristics play on predicting persons who are at greatest risk of developing arthritis in one or more joints. The authors have noted a lost-to-followup rate of 26%. Why is this cause for concern?   It is cause for concern because those who remain in the study may be at a systematically higher risk than those not followed   It is not cause for concern in this type of study; the concern exists only for randomized trials   It is cause for concern because those who remain in the study may be at a systematically higher or lower risk than those not followed   It is cause for concern because those who remain in the study may be at a systematically lower risk than those not followed

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Consider a study designed to estimate the role that certain characteristics play on predicting persons who are at greatest risk of developing arthritis in one or more joints. The authors have noted a lost-to-followup rate of 26%. Why is this cause for concern?

 

It is cause for concern because those who remain in the study may be at a systematically higher risk than those not followed

 

It is not cause for concern in this type of study; the concern exists only for randomized trials

 

It is cause for concern because those who remain in the study may be at a systematically higher or lower risk than those not followed

 

It is cause for concern because those who remain in the study may be at a systematically lower risk than those not followed

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