Consider a small protein containing 101 amino acid residues. The proteinbackbone will have 200 bonds about which rotation can occur. Assume thatthree orientations are possible about each of these bonds.(a) Based on these assumptions, about how many random-coil conformationswill be possible for this protein?(b) The estimate obtained in (a) is surely too large. Give one reason why.

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Chapter1: Biochemistry: An Evolving Science
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Consider a small protein containing 101 amino acid residues. The protein
backbone will have 200 bonds about which rotation can occur. Assume that
three orientations are possible about each of these bonds.
(a) Based on these assumptions, about how many random-coil conformations
will be possible for this protein?
(b) The estimate obtained in (a) is surely too large. Give one reason why.

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