Complete the pathway below by writing the intermediate (I) name, pathway name (P) and enzyme (E) name.
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Complete the pathway below by writing the intermediate (I) name, pathway name (P) and enzyme (E) name.
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- Two of the steps in the oxidative decarboxylation of pyruvate (steps 4 and 5 in the figure) do not involve any of the three carbons of pyruvate, yet are essential to the operation of the pyruvate dehydrogenase (PDH) complex. CH3 Pyruvate Hydroxyethyl TPP 1 TPP TPP CHOH 1 CH3 2 Pyruvate dehydrogenase, E₁ CH3 SH Acetyl lipoyllysine 515 CoA-SH CH3- C-S-COA Acetyl-CoA Oxidized lipoyllysine. Reduced 3 lipoyllysine Dihydrolipoyl transacetylase, E₂ Lys FAD -SH SH FADH₂ Dihydrolipoyl dehydrogenase, E3 NADH + H+ NAD+The metabolic precursor for the production of most eicosanoids isKindly answer numbers 4, 5 and 61. The metabolic precursor for the production of most eicosanoids isa. Cholesterolb. Sphingosinec. Arachidonic acidd. Eicosapentanoic acids2. Aspirin reduces inflammation and fever by inhibiting the formation of which of the following types of messenger lipids?a. Prostaglandins; Thromboxanesb. Thromboxanes; Prostaglandinsc. Leukotrienes; Thromboxanesd. Progestins; Prostaglandins3. Which of the following is a correct pairing of concepts?a. Male sex hormones: androgensb. Pregnancy hormones: estrogenc. Female sex hormones: progestinsd. After menopause hormones: estradiol 4. Which of the following substances is associated with Na+/K+ balance in the human body?a. Cortisolb. Cortisonec. Aldosteroned. Prednisolone5. Which of the following statements concerning steroid hormones is correct?a. Some, but not all of them, are cholesterol derivatives.b. Some, but not all of them, are glucose derivatives.c. Some, but not all of them, are fatty acid derivatives.d. All…
- Refer to Figure 3 which shows the relationship between phosphofuctokinase-1 (PFK-1) activity and fructose 2,6-bisphosphate. 100 +F2,6BP 80 60 40 -F2,6BP 20 0.05 0.1 0.2 0.4 0.7 1.0 2.0 4.0 EFructose 6-phosphate] (mm) Figure 3 (i) Explain the PFK-1 activity in the absence and presence of fructose 2, 6- bisphosphate. (ii) Explain the effect of increased ATP on PFK-I PFK-1 activity (% of Vma)In the presence of saturating amounts of oxaloacetate, the activity of citrate synthase from pig heart tissue shows a sigmoid dependence on the concentration of acetyl‑CoA. When succinyl‑CoA is added, the curve shifts to the right and the sigmoid dependence is more pronounced.Which statement on the biosynthesis of cannabinoids is NOT TRUE? Select one: O a. Geranyl pyrophosphate is formed as a precursor via the deoxyxylulose pathway in cannabis O b. Divarinic acid is the precursor for the production of propyl cannabinoid acids. O C. When prenyl-transferase enzyme uses olivetolic acid as substrate cannabigerivarinic acid (CBGVA) is formed. O d. THCA-synthase, CBDA-synthase, and CBC- synthase enzymes can use both CBGA and GBGVA as substrate.
- Compare and contrast the following items related to lipid metabolism. Cite their main similarities/or differences. 1.lysophosphatidylcholine vs. phosphatidylethanolamine 2.trimyristin vs. triolein. 3. ACP vs. carnitine-acyl transferase.The antidiabetes drugs known as thiazolidinediones induce the production of glycerol kinase in adipocytes. Explain why this would decrease the concentration of serum fatty acids, which are often elevated in diabetics.What is the effect of a defective a(1→ 4) phosphatase in Pompe's disease (GSD II)? O Accumulation of abnormal, unbranched glycogen, leading to heart or liver failure and short fife expectancy O Glycogen accumulation in heart, leading to heart failure, muscle weakness, short life expectancy O Absence of UDP-glucose conversion to glycogen, leading to lack of muscle glycogen, exercise intolerance Glycogen accumulation due to lack of glucose-6-phosphate conversion to glucose, leading to liver enlargement, hypoglycemia, short life expectancy O Lack of complete degradation of glycogen to glucose. leading to mild hypoglycemia, enlarged liver and muscle weakness Submit Request Answer
- Write the structure of each nucleotide-linked sugar in the pathway shown in Figure1. The second high energy intermediate metabolite of glycolysis that can be used for substrate level phosphorylation is also a precursor molecule for the synthesis of several amino acids. Name 5 of these amino acids. 2. Explain the indirect effect that allosteric effectors have on pyruvate dehydrogenase activity through phosphorylation/dephosphorylation of components within the PDH-complex.Folate deficiency in a cancer patient being treated with 5-Fluorouracil will lead to diminished capacity of this drug to inhibit thymidylate synthase. Group of answer choices True False