Macmillan Learning+NaOH,NaBr_NaBr, –IOStep 3: Complete the structure of thehaloamide, and use curved arrows to showthe conversion to the haloamidate in thenext step.Select Draw Templates More(+CHBr N Na 0HNa +LO!Erase:0 HQ2 QStep 5: Complete the structure ofthe isocyanate.Select Draw Templates More/||||||| C N0Erase11Step 4: Use three curved arrows to show therearrangement to form the isocyanate.Select Draw Templates MoreQH₂OсBr N Na 0:0 HHNaOErase2 QThe isocyanate is subsequently hydrated with water to formthe carbamic acid, which then decomposes to the amine andcarbon dioxide.NH₂0"] Organic ChemistryMaxwellpresented by Macmillan LearningComplete the mechanism of the Hofmann rearrangement that occurs when the given amide is treated with sodium hydroxideand bromine. Add any missing atoms, bonds, charges, nonbonding electron pairs, and curved arrows. Do not delete any of thepre-drawn bonds, charges, or electrons.Step 1: Complete the mechanism of the initial step ofthe reaction of the amide with sodium hydroxide toform the amidate by adding curved arrows.Select Draw Templates More/ |||||| сH N NaNaIHHOHEraseQ2Q11Step 2: The amidate then reacts with bromine toform the haloamide. Use curved arrows to showthe reaction with bromine.Select Draw Templates More/ ||||||||| C→Naс H:0 - HIHN:Br N1HNa: Br BrEraseOQ2 Q

Amides react with NaOH and Br2 to form amines with one carbon less than the parent amide. The…

Complete the mechanism of the Hofmann rearrangement that occurs when the given amide is treated with sodium hydroxide and bromine. Add any missing atoms, bonds, charges, nonbonding electron pairs, and curved arrows. Do not delete any of the pre-drawn bonds, charges, or electrons. Step 1: Complete the mechanism of the initial step of the reaction of the amide with sodium hydroxide to form the amidate by adding curved arrows. Select Draw Templates More / |||||| с H N Na Na+ | H O :0 - Erase Q2Q 11 Step 2: The amidate then reacts with bromine to form the haloamide. Use curved arrows to show the reaction with bromine. Select Draw Templates More / |||||| Na + с H Br N Na :0 H I H I H : Br I :: Br Erase 0 Q2Q

Complete the mechanism of the Hofmann rearrangement that occurs when the given amide is treated with sodium hydroxide and bromine. Add any missing atoms, bonds, charges, nonbonding electron pairs, and curved arrows. Do not delete any of the pre-drawn bonds, charges, or electrons. Step 1: Complete the mechanism of the initial step of the reaction of the amide with sodium hydroxide to form the amidate by adding curved arrows. Select Draw Templates More / |||||| с H N Na Na+ | H O :0 - Erase Q2Q 11 Step 2: The amidate then reacts with bromine to form the haloamide. Use curved arrows to show the reaction with bromine. Select Draw Templates More / |||||| Na + с H Br N Na :0 H I H I H : Br I :: Br Erase 0 Q2Q

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Concept explainers

Aldehydes and Ketones

Aldehydes and ketones are organic compounds that have a carbonyl group, C = O, as their functional group. They both differ in the placement of this carbonyl group in their structures.

Question

Macmillan Learning
+NaOH,
NaBr
_NaBr, –IO
Step 3: Complete the structure of the
haloamide, and use curved arrows to show
the conversion to the haloamidate in the
next step.
Select Draw Templates More
(+
CHBr N Na 0
H
Na +
LO!
Erase
:0 H
Q2 Q
Step 5: Complete the structure of
the isocyanate.
Select Draw Templates More
/||||||| C N
0
Erase
11
Step 4: Use three curved arrows to show the
rearrangement to form the isocyanate.
Select Draw Templates More
Q
H₂O
с
Br N Na 0
:0 H
H
Na
O
Erase
2 Q
The isocyanate is subsequently hydrated with water to form
the carbamic acid, which then decomposes to the amine and
carbon dioxide.
NH₂
0"]

Organic Chemistry
Maxwell
presented by Macmillan Learning
Complete the mechanism of the Hofmann rearrangement that occurs when the given amide is treated with sodium hydroxide
and bromine. Add any missing atoms, bonds, charges, nonbonding electron pairs, and curved arrows. Do not delete any of the
pre-drawn bonds, charges, or electrons.
Step 1: Complete the mechanism of the initial step of
the reaction of the amide with sodium hydroxide to
form the amidate by adding curved arrows.
Select Draw Templates More
/ |||||| с
H N Na
Na
I
H
H
O
H
Erase
Q2Q
11
Step 2: The amidate then reacts with bromine to
form the haloamide. Use curved arrows to show
the reaction with bromine.
Select Draw Templates More
/ ||||||||| C
→
Na
с H
:0 - H
I
H
N:
Br N
1
H
Na
: Br Br
Erase
O
Q2 Q

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