Compare and contrast the neural plasticity mechanisms of synaptic depression & synaptic facilitation. How many neurons are involved in these plasticity mechanisms, i.e. homosynaptic vs. heterosynaptic? You should discuss frequency of action potentials in the first neuron, any activity of other neurons, and effects on amplitude of graded potentials in the final neuron in the series. Is the final neuron more or less likely to produce action potentials following the activation of each plasticity mechanism?

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### Neural Plasticity Mechanisms: Synaptic Depression vs. Synaptic Facilitation

1. **Compare and contrast the neural plasticity mechanisms of synaptic depression & synaptic facilitation. How many neurons are involved in these plasticity mechanisms, i.e., homosynaptic vs. heterosynaptic?**
   
   To fully understand these mechanisms, consider the following aspects:
  
    - **Frequency of Action Potentials in the First Neuron:** Discuss how often the first neuron in the pathway fires action potentials and how this frequency affects synaptic activity.
    - **Activity of Other Neurons:** Consider how other neurons in the network might contribute to or modulate the synaptic plasticity being studied.
    - **Amplitude of Graded Potentials in the Final Neuron:** Analyze the changes in the strength or amplitude of the graded potentials in the final neuron within the series and how this affects neural output.
    - **Likelihood of Producing Action Potentials:** Determine whether the final neuron is more or less likely to generate action potentials after the activation of each type of plasticity mechanism.

Understanding these elements will provide a comprehensive comparison of synaptic depression and synaptic facilitation in neural plasticity processes.
Transcribed Image Text:### Neural Plasticity Mechanisms: Synaptic Depression vs. Synaptic Facilitation 1. **Compare and contrast the neural plasticity mechanisms of synaptic depression & synaptic facilitation. How many neurons are involved in these plasticity mechanisms, i.e., homosynaptic vs. heterosynaptic?** To fully understand these mechanisms, consider the following aspects: - **Frequency of Action Potentials in the First Neuron:** Discuss how often the first neuron in the pathway fires action potentials and how this frequency affects synaptic activity. - **Activity of Other Neurons:** Consider how other neurons in the network might contribute to or modulate the synaptic plasticity being studied. - **Amplitude of Graded Potentials in the Final Neuron:** Analyze the changes in the strength or amplitude of the graded potentials in the final neuron within the series and how this affects neural output. - **Likelihood of Producing Action Potentials:** Determine whether the final neuron is more or less likely to generate action potentials after the activation of each type of plasticity mechanism. Understanding these elements will provide a comprehensive comparison of synaptic depression and synaptic facilitation in neural plasticity processes.
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