Column chromatography was performed on a mixture containing compounds A, B and C using silica gel as a stationary phase and a 50:50 mixture of ethyl acetate:petroleum ether as the mobile phase. Six individual fractions were collected during the separation, and TLC analysis of the fractions provided the data shown. Evaluate and explain whether this column was successful in separating compounds A, B and C. If the column was not successful, suggest what changes could be made to provide a successful separation of this mixture. 1 2 3 4 5 6
Column chromatography was performed on a mixture containing compounds A, B and C using silica gel as a stationary phase and a 50:50 mixture of ethyl acetate:petroleum ether as the mobile phase. Six individual fractions were collected during the separation, and TLC analysis of the fractions provided the data shown. Evaluate and explain whether this column was successful in separating compounds A, B and C. If the column was not successful, suggest what changes could be made to provide a successful separation of this mixture. 1 2 3 4 5 6
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Column chromatography was performed on
a mixture containing compounds A, B and C
using silica gel as a stationary phase and a
50:50 mixture of ethyl acetate:petroleum ether
as the mobile phase. Six individual fractions
were collected during the separation, and
TLC analysis of the fractions provided the
data shown. Evaluate and explain whether
this column was successful in separating
compounds A, B and C. If the column was not
successful, suggest what changes could be
made to provide a successful separation of this
mixture.
1 2 3 4 5 6
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