Clostridium tetanomorphum glutamate is fermented by the following reaction sequence: (a) glutamate is converted to -methylaspartate (2-amino-3-methylsuccinate

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Chapter1: Biochemistry: An Evolving Science
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) In Clostridium tetanomorphum glutamate is fermented by the following reaction sequence: (a) glutamate is converted
to -methylaspartate (2-amino-3-methylsuccinate); (b) ammonia is released by an elimination reaction to produce
mesaconate {trans-HO2CCHC(CH3)CO2H}; (c) mesaconate is hydrated; and (d) the last reaction involves the cleavage
to pyruvate and acetate. Outline the above pathway, show structures, and indicate any cofactors (free or enzyme bound). 

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