Circle all chiral centers in ritonavir, drawn below, which is an antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS. HO IZ ZI S N

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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**Text Transcription for Educational Website:**

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**Title: Identifying Chiral Centers in Ritonavir**

**Description:**

Circle all chiral centers in ritonavir, drawn below, which is an antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS.

**Diagram Explanation:**

The image displays the chemical structure of ritonavir. This structure consists of several connected rings and chains, including multiple heteroatoms such as sulfur (S), nitrogen (N), and oxygen (O), each contributing to the drug's biological activity. The focus here is on identifying the chiral centers within this complex molecule. 

**Components of the Structure:**

- **Benzene Rings:** There are two benzene rings present, which are aromatic and contribute to the drug's stability.
- **Functional Groups:** The structure includes several functional groups like hydroxyl (OH) and amide groups, providing potential points of interaction with biological targets.
- **Chiral Centers:** Look for carbon atoms bonded to four different substituents. These chiral centers are crucial for the drug's function as they can affect how ritonavir interacts with the protease enzyme in HIV.

Students should be attentive to these structural elements while identifying the chiral centers within this chemical structure.

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This explanation offers an overview and guide for educational purposes, helping students understand the significance of chiral centers in pharmaceutical compounds like ritonavir.
Transcribed Image Text:**Text Transcription for Educational Website:** --- **Title: Identifying Chiral Centers in Ritonavir** **Description:** Circle all chiral centers in ritonavir, drawn below, which is an antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS. **Diagram Explanation:** The image displays the chemical structure of ritonavir. This structure consists of several connected rings and chains, including multiple heteroatoms such as sulfur (S), nitrogen (N), and oxygen (O), each contributing to the drug's biological activity. The focus here is on identifying the chiral centers within this complex molecule. **Components of the Structure:** - **Benzene Rings:** There are two benzene rings present, which are aromatic and contribute to the drug's stability. - **Functional Groups:** The structure includes several functional groups like hydroxyl (OH) and amide groups, providing potential points of interaction with biological targets. - **Chiral Centers:** Look for carbon atoms bonded to four different substituents. These chiral centers are crucial for the drug's function as they can affect how ritonavir interacts with the protease enzyme in HIV. Students should be attentive to these structural elements while identifying the chiral centers within this chemical structure. --- This explanation offers an overview and guide for educational purposes, helping students understand the significance of chiral centers in pharmaceutical compounds like ritonavir.
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