This image depicts a series of chemical reactions demonstrating various organic synthesis methods. Each reaction involves a specific starting compound, reagent(s), and conditions which lead to a specific chemical transformation. Below is a detailed transcription and explanation: **e)** - **Starting Compound:** Cyclopentanol with a methyl group (CH₃) attached to the ring. - **Reagent/Conditions:** 85% H₂SO₄ at 110°C. - **Reaction Type:** Likely an acid-catalyzed dehydration reaction leading to the formation of an alkene. **f)** - **Starting Compound:** A brominated cyclohexane derivative. - **Reagent/Conditions:** CH₃CH₂OH with AgNO₃ at room temperature. - **Reaction Type:** Nucleophilic substitution, where the bromine is likely replaced by an ethoxy group. **g)** - **Starting Compound:** An iodinated tertiary butyl compound. - **Reagent/Conditions:** Potassium tert-butoxide (KOC(CH₃)₃) in tert-butyl alcohol ((CH₃)₃COH) under heat (Δ). - **Reaction Type:** Elimination reaction, possibly leading to the formation of an alkene through the E2 mechanism. **h)** - **Starting Compound:** A cyclohexane ring with a bromine and a methyl substituent. - **Reagent/Conditions:** NaSCH₃ in DMSO. - **Reaction Type:** A nucleophilic substitution likely resulting in the replacement of bromine with a methylthio group. **i)** - **Starting Compound:** Benzyl methanesulfonate (CH₂OMs). - **Reagent/Conditions:** Sodium methoxide (NaOCH₃) in methanol, heated under reflux. - **Reaction Type:** Nucleophilic substitution, where the methanesulfonate group is likely replaced by a methoxide group. These reactions illustrate key principles in organic chemistry such as substitution and elimination mechanisms, and highlight the impact of different reagents and conditions on reaction pathways. **Description of Reactions and Mechanisms** **a)** Two equivalents of NaCN in acetone are used to react with a compound containing two iodines and two hydrogens bonded to a carbon chain: - **Reaction Type:** Nucleophilic substitution - **Mechanism:** Likely SN2 due to the presence of acetone as a polar aprotic solvent. **b)** A cyclohexane derivative with a chlorine and a methyl group is reacted with CH₃CH₂CH₂OH under warm conditions: - **Reaction Type:** Nucleophilic substitution or elimination - **Mechanism:** Possibly SN1 due to the alcohol as both a solvent and nucleophile, potentially leading to elimination if conditions favor it. **c)** An alkyl tosylate is reacted with NaOCH₃ in refluxing methanol: - **Reaction Type:** Nucleophilic substitution - **Mechanism:** SN2, as NaOCH₃ is a strong nucleophile and methanol is a polar protic solvent aiding in the substitution process. **d)** CH₃Cl reacts with NaNH₂ in ammonia: - **Reaction Type:** Elimination - **Mechanism:** E2, as NaNH₂ is a strong base, and NH₃ provides the necessary conditions for elimination to form an alkene. **e)** A cyclopentane alcohol derivative undergoes reaction with 85% H₂SO₄ at 110°C: - **Reaction Type:** Dehydration - **Mechanism:** E1, acid-catalyzed elimination resulting in an alkene through the dehydration of alcohol. **f)** An alkyl bromide is treated with CH₃CH₂OH and AgNO₃ at room temp: - **Reaction Type:** Nucleophilic substitution - **Mechanism:** SN1, as AgNO₃ can lead to the formation of a carbocation intermediate, facilitating substitution in the presence of ethanol. **g)** A methyl iodide derivative is reacted with KOC(CH₃)₃ in tert-butanol under heat: - **Reaction Type:** Elimination - **Mechanism:** E2, using KOC(CH₃)₃ as a strong base to promote elimination and the heat assisting in driving the reaction. These reactions involve a variety of nucleophilic substitutions and eliminations, showcasing the role of solvents, temperature,

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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Only g and h and i

 

 

This image depicts a series of chemical reactions demonstrating various organic synthesis methods. Each reaction involves a specific starting compound, reagent(s), and conditions which lead to a specific chemical transformation. Below is a detailed transcription and explanation:

**e)**
- **Starting Compound:** Cyclopentanol with a methyl group (CH₃) attached to the ring.
- **Reagent/Conditions:** 85% H₂SO₄ at 110°C.
- **Reaction Type:** Likely an acid-catalyzed dehydration reaction leading to the formation of an alkene.

**f)**
- **Starting Compound:** A brominated cyclohexane derivative.
- **Reagent/Conditions:** CH₃CH₂OH with AgNO₃ at room temperature.
- **Reaction Type:** Nucleophilic substitution, where the bromine is likely replaced by an ethoxy group.

**g)**
- **Starting Compound:** An iodinated tertiary butyl compound.
- **Reagent/Conditions:** Potassium tert-butoxide (KOC(CH₃)₃) in tert-butyl alcohol ((CH₃)₃COH) under heat (Δ).
- **Reaction Type:** Elimination reaction, possibly leading to the formation of an alkene through the E2 mechanism.

**h)**
- **Starting Compound:** A cyclohexane ring with a bromine and a methyl substituent.
- **Reagent/Conditions:** NaSCH₃ in DMSO.
- **Reaction Type:** A nucleophilic substitution likely resulting in the replacement of bromine with a methylthio group.

**i)**
- **Starting Compound:** Benzyl methanesulfonate (CH₂OMs).
- **Reagent/Conditions:** Sodium methoxide (NaOCH₃) in methanol, heated under reflux.
- **Reaction Type:** Nucleophilic substitution, where the methanesulfonate group is likely replaced by a methoxide group.

These reactions illustrate key principles in organic chemistry such as substitution and elimination mechanisms, and highlight the impact of different reagents and conditions on reaction pathways.
Transcribed Image Text:This image depicts a series of chemical reactions demonstrating various organic synthesis methods. Each reaction involves a specific starting compound, reagent(s), and conditions which lead to a specific chemical transformation. Below is a detailed transcription and explanation: **e)** - **Starting Compound:** Cyclopentanol with a methyl group (CH₃) attached to the ring. - **Reagent/Conditions:** 85% H₂SO₄ at 110°C. - **Reaction Type:** Likely an acid-catalyzed dehydration reaction leading to the formation of an alkene. **f)** - **Starting Compound:** A brominated cyclohexane derivative. - **Reagent/Conditions:** CH₃CH₂OH with AgNO₃ at room temperature. - **Reaction Type:** Nucleophilic substitution, where the bromine is likely replaced by an ethoxy group. **g)** - **Starting Compound:** An iodinated tertiary butyl compound. - **Reagent/Conditions:** Potassium tert-butoxide (KOC(CH₃)₃) in tert-butyl alcohol ((CH₃)₃COH) under heat (Δ). - **Reaction Type:** Elimination reaction, possibly leading to the formation of an alkene through the E2 mechanism. **h)** - **Starting Compound:** A cyclohexane ring with a bromine and a methyl substituent. - **Reagent/Conditions:** NaSCH₃ in DMSO. - **Reaction Type:** A nucleophilic substitution likely resulting in the replacement of bromine with a methylthio group. **i)** - **Starting Compound:** Benzyl methanesulfonate (CH₂OMs). - **Reagent/Conditions:** Sodium methoxide (NaOCH₃) in methanol, heated under reflux. - **Reaction Type:** Nucleophilic substitution, where the methanesulfonate group is likely replaced by a methoxide group. These reactions illustrate key principles in organic chemistry such as substitution and elimination mechanisms, and highlight the impact of different reagents and conditions on reaction pathways.
**Description of Reactions and Mechanisms**

**a)**  
Two equivalents of NaCN in acetone are used to react with a compound containing two iodines and two hydrogens bonded to a carbon chain:

- **Reaction Type:** Nucleophilic substitution
- **Mechanism:** Likely SN2 due to the presence of acetone as a polar aprotic solvent.

**b)**  
A cyclohexane derivative with a chlorine and a methyl group is reacted with CH₃CH₂CH₂OH under warm conditions:

- **Reaction Type:** Nucleophilic substitution or elimination
- **Mechanism:** Possibly SN1 due to the alcohol as both a solvent and nucleophile, potentially leading to elimination if conditions favor it.

**c)**  
An alkyl tosylate is reacted with NaOCH₃ in refluxing methanol:

- **Reaction Type:** Nucleophilic substitution
- **Mechanism:** SN2, as NaOCH₃ is a strong nucleophile and methanol is a polar protic solvent aiding in the substitution process.

**d)**  
CH₃Cl reacts with NaNH₂ in ammonia:

- **Reaction Type:** Elimination
- **Mechanism:** E2, as NaNH₂ is a strong base, and NH₃ provides the necessary conditions for elimination to form an alkene.

**e)**  
A cyclopentane alcohol derivative undergoes reaction with 85% H₂SO₄ at 110°C:

- **Reaction Type:** Dehydration
- **Mechanism:** E1, acid-catalyzed elimination resulting in an alkene through the dehydration of alcohol.

**f)**  
An alkyl bromide is treated with CH₃CH₂OH and AgNO₃ at room temp:

- **Reaction Type:** Nucleophilic substitution
- **Mechanism:** SN1, as AgNO₃ can lead to the formation of a carbocation intermediate, facilitating substitution in the presence of ethanol.

**g)**  
A methyl iodide derivative is reacted with KOC(CH₃)₃ in tert-butanol under heat:

- **Reaction Type:** Elimination
- **Mechanism:** E2, using KOC(CH₃)₃ as a strong base to promote elimination and the heat assisting in driving the reaction.

These reactions involve a variety of nucleophilic substitutions and eliminations, showcasing the role of solvents, temperature,
Transcribed Image Text:**Description of Reactions and Mechanisms** **a)** Two equivalents of NaCN in acetone are used to react with a compound containing two iodines and two hydrogens bonded to a carbon chain: - **Reaction Type:** Nucleophilic substitution - **Mechanism:** Likely SN2 due to the presence of acetone as a polar aprotic solvent. **b)** A cyclohexane derivative with a chlorine and a methyl group is reacted with CH₃CH₂CH₂OH under warm conditions: - **Reaction Type:** Nucleophilic substitution or elimination - **Mechanism:** Possibly SN1 due to the alcohol as both a solvent and nucleophile, potentially leading to elimination if conditions favor it. **c)** An alkyl tosylate is reacted with NaOCH₃ in refluxing methanol: - **Reaction Type:** Nucleophilic substitution - **Mechanism:** SN2, as NaOCH₃ is a strong nucleophile and methanol is a polar protic solvent aiding in the substitution process. **d)** CH₃Cl reacts with NaNH₂ in ammonia: - **Reaction Type:** Elimination - **Mechanism:** E2, as NaNH₂ is a strong base, and NH₃ provides the necessary conditions for elimination to form an alkene. **e)** A cyclopentane alcohol derivative undergoes reaction with 85% H₂SO₄ at 110°C: - **Reaction Type:** Dehydration - **Mechanism:** E1, acid-catalyzed elimination resulting in an alkene through the dehydration of alcohol. **f)** An alkyl bromide is treated with CH₃CH₂OH and AgNO₃ at room temp: - **Reaction Type:** Nucleophilic substitution - **Mechanism:** SN1, as AgNO₃ can lead to the formation of a carbocation intermediate, facilitating substitution in the presence of ethanol. **g)** A methyl iodide derivative is reacted with KOC(CH₃)₃ in tert-butanol under heat: - **Reaction Type:** Elimination - **Mechanism:** E2, using KOC(CH₃)₃ as a strong base to promote elimination and the heat assisting in driving the reaction. These reactions involve a variety of nucleophilic substitutions and eliminations, showcasing the role of solvents, temperature,
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