Preview File Edit 2022-08-13 12-45.pdf What s FR Join In (11) Join In (13) What sence of rescents will accomplish the What sequence of reagents will accomplish the following transformat o 2140 KO HO 140² Problem 18.38 . A step in a synthesis of POE, (prostaglandin E alprostadil) is the reaction of a trisubstituted cycloheme with bromine to form a bromolactone 12 Example 18.11-Solution 13 +-1914 Join In (12) - What is the expected product for the following Join In (14) 14 ia www Join In (16) 15 Predict the product of the following reaction 1. Identify the compound that will react fastest when heated in aqueous NaOH None of these itasard 2° 1. The stereochemistry is fixed by the bicyclic The bromine atom is axial, while the-CCOO and View Go 2,568 V Sort By: Tools Window Help 2022-08-13 12-45.pdf Page 13 of 15 2. 1. Search Rank 3. H* Page Order What sequence of reagents will accomplish the following transformation? CH3OH 2 PhMgBr Et₂O H* PhOH AUG 14 LOH 2 PhMgBr Et₂0 H3O+ H3O+ tv NA 4. 8 5. H* OH CH3OH SOCI₂ 411 Dights Reserved Search 2 PhOH 2 PhOH Sun Aug 14 12:03 PM X Done M M M g V ng ov g OV g ov

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please explain which reganets and why show step by step please

Preview File Edit
2022-08-13 12-45.pdf
What s
FR
Join In (11)
Join In (13)
What sence of rescents will accomplish the
What sequence of reagents will accomplish the
following transformat
o
2140
KO
HO
140²
Problem 18.38
. A step in a synthesis of POE, (prostaglandin E
alprostadil) is the reaction of a trisubstituted
cycloheme with bromine to form a bromolactone
12
Example 18.11-Solution
13
+-1914
Join In (12)
- What is the expected product for the following
Join In (14)
14
ia
www
Join In (16)
15
Predict the product of the following reaction
1.
Identify the compound that will react fastest when
heated in aqueous NaOH
None of these
itasard
2°
1.
The stereochemistry is fixed by the bicyclic
The bromine atom is axial, while the-CCOO and
View Go
2,568
V
Sort By:
Tools Window Help
2022-08-13 12-45.pdf
Page 13 of 15
2.
1.
Search Rank
3.
H*
Page Order
What sequence of reagents will accomplish the
following transformation?
CH3OH
2 PhMgBr
Et₂O
H*
PhOH
AUG
14
LOH
2 PhMgBr
Et₂0
H3O+
H3O+
tv NA
4.
8
5.
H*
OH
CH3OH
SOCI₂
411 Dights Reserved
Search
2 PhOH
2 PhOH
Sun Aug 14 12:03 PM
X
Done
M
M
M
g
V
ng
ov
g
OV
g
ov
Transcribed Image Text:Preview File Edit 2022-08-13 12-45.pdf What s FR Join In (11) Join In (13) What sence of rescents will accomplish the What sequence of reagents will accomplish the following transformat o 2140 KO HO 140² Problem 18.38 . A step in a synthesis of POE, (prostaglandin E alprostadil) is the reaction of a trisubstituted cycloheme with bromine to form a bromolactone 12 Example 18.11-Solution 13 +-1914 Join In (12) - What is the expected product for the following Join In (14) 14 ia www Join In (16) 15 Predict the product of the following reaction 1. Identify the compound that will react fastest when heated in aqueous NaOH None of these itasard 2° 1. The stereochemistry is fixed by the bicyclic The bromine atom is axial, while the-CCOO and View Go 2,568 V Sort By: Tools Window Help 2022-08-13 12-45.pdf Page 13 of 15 2. 1. Search Rank 3. H* Page Order What sequence of reagents will accomplish the following transformation? CH3OH 2 PhMgBr Et₂O H* PhOH AUG 14 LOH 2 PhMgBr Et₂0 H3O+ H3O+ tv NA 4. 8 5. H* OH CH3OH SOCI₂ 411 Dights Reserved Search 2 PhOH 2 PhOH Sun Aug 14 12:03 PM X Done M M M g V ng ov g OV g ov
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