. What sequence of reagents will accomplish the following transformation? O 1. 2. 3. HCI H₂O H₂O NH₂ SOCI₂ HCI 4. 5. H3O+ SOCI₂ CI SOCI₂

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explain which reagents and why

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2022-08-13 12-45.pdf
What sen
Join In (11)
JO
Join In (13)
What sequence of reagents will accomplish the
What sogance of reagents will accomplish the
following and
o
HO
140
Problem 18.38
. A step in a synthesis of POE, (prostaglandin E
alprostadil) is the reaction of a trisubstituted
cycloheme with bromine to form a bromolactone
-Propachain for formation of this bemolactone and
Problem 18.38-Solution
File Edit
CO
12
13
+-1914
Join In (12)
14
Join In (14)
www
15
ia
What is the expected product for the following
Join In (16)
Predict the product of the following reaction
TUAH
1.
Identify the compound that will react fastest when
heated in aqueous NaOH
1.
The stereochemistry is fixed by the bicyclic
The bromine atom is axial, while the-CCOO and
itasard
View Go
2,568
V
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2022-08-13 12-45.pdf
Page 14 of 15
.
Search Rank
Join In (15)
Page Order
1.
2.
What sequence of reagents will accomplish the
following transformation?
O
HCI
H₂O
3. H₂O
AUG
14
NH₂
SOCI2
HCI
tv NA
4.
5.
8
O
H3O+
V
SOCI₂
CI
Search
SOCI₂
Sun Aug 14 12:03 PM
X
Done
M
Joir
M
M
g
V
g
ov
g
DV
g
ov
Transcribed Image Text:Preview 2022-08-13 12-45.pdf What sen Join In (11) JO Join In (13) What sequence of reagents will accomplish the What sogance of reagents will accomplish the following and o HO 140 Problem 18.38 . A step in a synthesis of POE, (prostaglandin E alprostadil) is the reaction of a trisubstituted cycloheme with bromine to form a bromolactone -Propachain for formation of this bemolactone and Problem 18.38-Solution File Edit CO 12 13 +-1914 Join In (12) 14 Join In (14) www 15 ia What is the expected product for the following Join In (16) Predict the product of the following reaction TUAH 1. Identify the compound that will react fastest when heated in aqueous NaOH 1. The stereochemistry is fixed by the bicyclic The bromine atom is axial, while the-CCOO and itasard View Go 2,568 V Sort By: Tools Window Help 2022-08-13 12-45.pdf Page 14 of 15 . Search Rank Join In (15) Page Order 1. 2. What sequence of reagents will accomplish the following transformation? O HCI H₂O 3. H₂O AUG 14 NH₂ SOCI2 HCI tv NA 4. 5. 8 O H3O+ V SOCI₂ CI Search SOCI₂ Sun Aug 14 12:03 PM X Done M Joir M M g V g ov g DV g ov
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