Case:  A prescription for calls for compounding 60 mL of an oral solution for patient A.  This oral solution contains 45 mg of salicylic acid. The pharmacist decides to weigh this on a balance with a minimum weighable quantity of 120 mg and dissolve it an appropriate solvent to prepare the solution. Answer the following questions to explain how you will use the liquid measurement aliquot method to obtain the correct amount of salicylic acid to prepare this solution. When making this preparation, you want to minimize the amount of salicylic acid that is wasted.  The prescription is as follows:   Rx  Salicylic acid                            45 mg       Cherry flavor solution             5 mL       Ora-Syrupee                qs        60 mL   What is the target amount of salicylic acid for the liquid aliquot that will be used to make the 60 mL oral solution?     What is the maximum volume of the liquid aliquot can be used to make this preparation?       If you weigh 120 mg of salicylic acid on your balance and want to use an aliquot volume of 15 mL, how much solvent will you use to dissolve the 120 mg of salicylic acid.

Chemistry: Principles and Practice
3rd Edition
ISBN:9780534420123
Author:Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
Publisher:Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
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  1. Case:  A prescription for calls for compounding 60 mL of an oral solution for patient A.  This oral solution contains 45 mg of salicylic acid. The pharmacist decides to weigh this on a balance with a minimum weighable quantity of 120 mg and dissolve it an appropriate solvent to prepare the solution. Answer the following questions to explain how you will use the liquid measurement aliquot method to obtain the correct amount of salicylic acid to prepare this solution. When making this preparation, you want to minimize the amount of salicylic acid that is wasted.  The prescription is as follows:

 

Rx  Salicylic acid                            45 mg

      Cherry flavor solution             5 mL

      Ora-Syrupee                qs        60 mL

 

  1. What is the target amount of salicylic acid for the liquid aliquot that will be used to make the 60 mL oral solution?

 

 

  1. What is the maximum volume of the liquid aliquot can be used to make this preparation?

 

 

 

  1. If you weigh 120 mg of salicylic acid on your balance and want to use an aliquot volume of 15 mL, how much solvent will you use to dissolve the 120 mg of salicylic acid.

 

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