Carter et al investigated the effect of age at onset of bipolar disorder on the course of the illness. One of the variables studied was the subjects' family history. The table below shows the frequency of a family history of mood disorders in the two groups of interest: early age at onset (18 years or younger) and later age at onset (later than 18 years old). Can we conclude on the basis of these data that subjects 18 or younger differ from subjects older than 18 with respect to family histories of mood disorders? Ref: J Psychiatric Research 37(2003), 297-303.

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Carter et al investigated the effect of age at onset of bipolar disorder on the course of the illness. One of the variables studied was the subjects' family history. The table below shows the frequency of a family history of mood disorders in the two groups of interest: early age at onset (18
years or younger) and later age at onset (later than 18 years old). Can we conclude on the basis of these data that subjects 18 or younger differ from subjects older than 18 with respect to family histories of
mood disorders? Ref: J Psychiatric Research 37(2003), 297-303.

**Table: Family History of Mood Disorders and Age of Onset**

This table presents data on individuals categorized by their family history of mood disorders and the age at which they first experienced symptoms. The table is divided into two main columns based on the age of onset: Early (≤18 years) and Later (>18 years). A total count for each category and overall sums are also provided.

- **Family History of Mood Disorders**:
  - **None (A)**: 
    - Early ≤18 (E): 28 individuals
    - Later >18 (L): 35 individuals
    - Total: 63 individuals
  - **Bipolar Disorder (B)**:
    - Early ≤18 (E): 19 individuals
    - Later >18 (L): 38 individuals
    - Total: 57 individuals
  - **Unipolar Disorder (C)**:
    - Early ≤18 (E): 41 individuals
    - Later >18 (L): 44 individuals
    - Total: 85 individuals
  - **Unipolar and Bipolar (D)**:
    - Early ≤18 (E): 53 individuals
    - Later >18 (L): 60 individuals
    - Total: 113 individuals

- **Total Counts**:
  - Early ≤18 (E): 141 individuals
  - Later >18 (L): 177 individuals
  - Overall Total: 318 individuals

This data is valuable for understanding the distribution of mood disorder prevalence with respect to age and family history.
Transcribed Image Text:**Table: Family History of Mood Disorders and Age of Onset** This table presents data on individuals categorized by their family history of mood disorders and the age at which they first experienced symptoms. The table is divided into two main columns based on the age of onset: Early (≤18 years) and Later (>18 years). A total count for each category and overall sums are also provided. - **Family History of Mood Disorders**: - **None (A)**: - Early ≤18 (E): 28 individuals - Later >18 (L): 35 individuals - Total: 63 individuals - **Bipolar Disorder (B)**: - Early ≤18 (E): 19 individuals - Later >18 (L): 38 individuals - Total: 57 individuals - **Unipolar Disorder (C)**: - Early ≤18 (E): 41 individuals - Later >18 (L): 44 individuals - Total: 85 individuals - **Unipolar and Bipolar (D)**: - Early ≤18 (E): 53 individuals - Later >18 (L): 60 individuals - Total: 113 individuals - **Total Counts**: - Early ≤18 (E): 141 individuals - Later >18 (L): 177 individuals - Overall Total: 318 individuals This data is valuable for understanding the distribution of mood disorder prevalence with respect to age and family history.
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