Carboxylation of acetyl CoA to produce malonyl CoA is catalyzed by a. Malonyl COA carboxylase
Q: Malonyl-CoA synthesized by the action of acetyl-CoA carboxylase II is primarily used: a. To…
A: Acetyl CoA is produced in mitochondria and cannot leave mitochondria so it combines with…
Q: If Acetyl CoA is converted to a ketone, it is likely that which of the following is undergoing…
A: more then one option is correct. Correct answer are oxaloacetate and fatty acids. Incorrect one are…
Q: Please explain the role of pantothenic acid-derived CoA as a carrier of acetyl group in carbohydrate…
A: Coenzyme A is required for the metabolism of carbohydrates. Pantothenic acid is the prescursor of…
Q: Many components of the glycolytic pathway and the citricacid cycle are direct exit or entry points…
A: Note: Since you have posted a question with multiple subparts, we will solve the first three…
Q: After the formation of pyruvic acid it must be converted into Acetyl CoA to enter the Krebs cycle…
A: Cellular respiration involves breakdown of glucose through a series of catabolic steps in the cell…
Q: Select the INCORRECT statement about Glutamate dehydrogenase : a. Catalyzes the removal of NH4+…
A: Enzymes are involved in increasing the rate of a biological reaction by lowering the activation…
Q: Which of the following a. phosphopentose isomerase b. acetyl CoA carboxylase c. isocitrate…
A: glycolysis : phosphofructokinase Glucose 6 phosphate dehydrogenase : pentose phosphate…
Q: β-oxidation is inhibited by A. high acetyl-CoA levels B. low malonyl-CoA levels C.…
A: Beta-oxidation is the process of fatty acid degradation to remove the fragments of carbon atoms…
Q: During fatty acid biosynthesis, propionyl CoA is the donor of the acetyl group. O True O False
A: Fatty acid biosynthesis occurs in the cytoplasm and endoplasmic reticulum of the cell. They are…
Q: CO2 is released when A. creating a thioester bond between acetyl-CoA and acyl-carrier protein…
A: Fatty acid biosynthesis occurs in the cytosol. Beta-oxidation occurs in the mitochondrial matrix.…
Q: Not all of the acetyl-CoA from the mitochondria is carboxylated to malonyl-CoA because some are used…
A: Mitochondria is the powerhouse of the cell. Acetyl CoA cannot cross the mitochondrial membrane.…
Q: After several days of starvation, the ability of the liver to metabolize acetyl-CoA via the citric…
A: During starvation, glycogen stored as a fuel is used up by the liver to supply the required amount…
Q: Explain the importance to lipid metabolism of phosphorylation by Protein Kinase A using the…
A: During fasting or exercise, the triglycerides in adipose tissues are hydrolyzed into fatty acids and…
Q: Five coenzymes are required by a-ketoglutarate dehydrogenase, the enzyme in the citric acid cycle…
A: Krebs cycle (also known as the citric acid cycle or tricarboxylic acid cycle). This cycle occurs in…
Q: In the context of fatty acid oxidation to acetyl CoA, indicate whether each of the following…
A: The fatty acid oxidation occurs in the matric of mitochondria where the fatty acids get activated in…
Q: Under conditions of strenuous activity (anaerobic) the product is: acetyl CoA pyruvate lactate
A: Ans- lactate
Q: The PDH mechanism coenzyme that plays a direct role in the generation of acetyl CoA is NADH…
A: PDH means pyruvate dehydrogenase complex. This enzyme has three subunits named pyruvate…
Q: following metabolite negatively regulates pyruvate kinase? Select one: a. Fructose-1,6-Bisphosphate…
A: It is essential to regulate metabolic pathways because all are interconnected to each other. Hence,…
Q: (a) Indicate the steps involved in its oxidation to acetyl-CoA and/or other products (NADH, FADH2,…
A: Beta oxidation of FA is a metabolism of FA which is a cyclic process and at each step one…
Q: A biological Claisen reaction occurs in the conversion of two acetyl CoA molecules to one…
A: Introduction: The condensation reactions involve the formation of new carbon-carbon bonds. The most…
Q: Five coenzymes are required by a-ketoglutarate dehydrogenase, the enzyme in the citric acid cycle…
A: The citric acid cycle is also called as TCA cycle is a series of chemical reactions used by all…
Q: state, which of the following occur(s)? a) insulin stimulation of malonyl CoA formatio
A: The fed state takes place after a meal when the body is starting to digest the food ingested and…
Q: Release of Acetyl CoA from the ketoacy| CoA is catalyzed by
A: First question answer is option c- thiolases,
Q: Most aminotransferases are specific for the keto acid a. a-ketoglutarate b. oxaloacetate c. pyruvate…
A: Transaminases or Aminotransferases Aminotransferases are the enzymes which catalyse the reactions…
Q: Citrate Synthase exists as a dimer but can catalyze the formation of only 1 citrate from Acetyl-CoA…
A: The formation of citrate from Acetyl- CoA, and Oxaloacetate is catalyzed by the enzyme citrate…
Q: Order the steps that results in a triacylglycerol containing two palmitic acids and one stearic…
A: The below steps are involved in fatty acid synthesis- two palmitic and one stearic acid containing…
Q: The sources of the three (3) carbons in malonyl-Coa is/are: a. 1 C from C02 and 2 C from acetyl-CoA…
A: Malonyl-CoA is one of the major molecules and are involved in fatty acid biosynthesis .
Q: Acetyl-CoA carboxylase is inhibited by A. biotin B. citrate C. acetyl-CoA D.…
A: Acetyl-CoA carboxylase (ACC) catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA, an…
Q: Lysine is degraded to acetoacetyl-CoA then to acetyl-CoA, and is described as a _______ amino…
A: Lysine and arginine are broken down into acetoacetyl CoA and Acetyl CoA respectively. The process…
Q: Explain why with complete examples: A- Partial carbocation formation B- Acetyl CoA has many fates
A: Partial carbocation: Carbocations are nothing but positively charged carbon atoms. Under normal…
Q: Degradation of fats as an energy source involves all of the following excepta) β -oxidation.b)…
A: Fatty acid metabolism involves various metabolic processes related to fatty acids. Fatty acids are…
Q: Which of the following is NOT a fate of acetyl-CoA in mammals? a. Is used to synthesize cholesterol…
A:
Q: Thiolase is homologous in structure to the condensing enzyme. On the basis of this observation,…
A: Thiolases are enzymes that are involved in the mevalonate pathway. They convert two units of…
Q: When transaminated, the three branched-chain amino acids (valine, leucine, and isoleucine) form…
A: Maple syrup urine disease is an autosomal recessive disorder. It results from the deficiency of…
Q: Which cofactor is essential for the synthesis of arginine in bacteria A. Tetrahydrofolate B.…
A: Biochemistry is the science of study of the internal biochemical processes of organisms. The…
Q: Describe the synthesis of palmitic acid starting from acetyl CoA and malonyl-CoA.
A: Palmitic acid, or hexadecanoic acid in IUPAC nomenclature, is the most common saturated fatty acid…
Q: Suggest a name for an enzyme that catalyzes each of t a.) Oxidation of nitrite b.) Decarboxylation…
A: An enzyme is a substance that acts as a catalyst in living organisms, regulating the rate at which…
Q: To begin the TCA cycle, pyruvate must be converted into acetyl-Coenzyme A (acetyl-CoA) by the enzyme…
A: The TCA cycle is at the center of cellular metabolism, playing a starring role in both the process…
Q: _______________ is an intermediate metabolite linkage between carbohydrate and fat metabolism. A.…
A: ATP is the chief molecule that provides energy when the high energy in the ATP molecules is removed…
Q: CHOOSE THE CORRECT LETTER 1. Condensation of acetyl CoA with oxaloacetate is catalyzed by A. citrate…
A: The citric acid cycle involves the oxidation of acetyl CoA to CO2 and H2O. The cycle starts with the…
Q: What enzyme(s) is/are specifically required for the oxidation of a Aeven monounsaturated fatty acid?…
A: Enzymes are a class of proteins that are also known as biological catalysts or biocatalysts for…
Q: Statin drugs are used to treat hypercholesterolemia because they a. prevent cholesterol from…
A: Hypercholesterolemia is a condition during which blood has a high level of cholesterol. This is…
Q: Mammals cannot undergo net synthesis of carbohydrate from acetyl-CoA, but the carbons of acetyl-CoA…
A: Glucose is catabolized to generate ATP by respiration. The carbon chain in glucose is oxidized and…
Q: Although glucose cannot be formed from acetyl-CoA, triglycerides can enter the glycolytic pathway…
A: Introduction Fats (or triglycerides) are ingested as food or synthesised by adipocytes or…
Q: In the pyruvae dehydrogensae complex, acetyl-coa is released by the dihydrolipoyl transacetylase…
A: Pyruvate dehydrogenase complex converts pyruvate to acetyl CoA by oxidative decarboxylation.…
Q: The carbon skeleton produced by the lysine deamination can produce: A)Oxaloacetate B)Acetyl-CoA…
A: Amino acids get degraded into glycolytic and TCA cycle intermediates which are further metabolized…
Q: If Acetyl-CoA carboxylase is used to catalyze the synthesis of malonyl-coA from acetyl-CoA and…
A: Palmitate is a saturated fatty acid made up of 16 carbons. It is synthesized from acetyl CoA by the…
Q: After three rounds of oxidation, the fatty acyl-CoA has been shortened by carbons due to the…
A: Oleic acid is an example of mono unsaturated fatty acid (MUFA) as it has a cis double bond between…
Q: In Yeast, pyruvate can be directly converted into: A. acetyl-CoA and ethanol B. acetyl-CoA only C.…
A: Pyruvate is made from the glycolysis of glucose, glycolysis breaks glucose into two pyruvate.…
Q: Release of Acetyl CoA from the ketoacy| CoA is catalyzed by a. Hydratase b.Lipoprotein lipase c.…
A: Biological macromolecules are those large molecules that are necessary for the survival and growth…
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- Which enzyme is used for both the synthesis and breakdown of acetoacetate? thiolase O HMG-CoA synthase OB-hydroxybutyrate dehydrogenase O B-Ketoacyl-CoA transferaseWhich of the followinga. phosphopentose isomeraseb. acetyl CoA carboxylasec. isocitrate dehydrogenased. fructose 1,6,biphosphatase-1e. glucose 6-phosphate dehydrogenaseis appropriate for this analogyglycolysis:phosphofructokinase-1:______:pentose phosphate pathwayUpon considering the complete oxidation of one mole of fatty acyl (CoA) of an arachidic acid (20:0). Answer the following lettersa. Rounds of beta oxidationb. total no. of acety CoA producedc. total no. of NADH produced from all rounds of beta oxidariond. total no. of FADH2 produced from all rounds of beta oxidation
- CHOOSE THE CORRECT LETTER 1.Which of the following enzymes catalyze the reaction involved in the production of FADHy in the Kreb's cycle?A. malate dehydrogenaseB. a-ketoglutarate dehydrogenaseC.isocitrate dehydrogenaseD. succinate dehydrogenase 2.Steric acid requires eight cycles of B-oxidation to be completely converted to acety/-CoA.A.TrueB. FalseWhich of the following transfers fatty acid from carnitine to CoA I.carnitine translocaseII.coenzyme-AIII.CPT-IIIV.CPT-IConsider the docosanoic acid, C21H43CO2H a. Label the a and B carbons b. Draw the acyl CoA derived from this fatty acid c. How many acetyl CoA molecules are formed by complete B-oxidation? d. How many cycles of B-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid?
- Which one of the following will function to inhibit CPT1? A.palmitoyl-CoA B.citrate C propionyl-CoA D.acetyl-CoA E malonyl-CoAGive the process/pathway where each of the following enzymes is involved. _______________________ a. HMG CoA lyase _______________________ b. HMG CoA reductase _______________________ c. Acetyl CoA carboxylase _______________________ d. Acyl CoA dehydrogenaseUsing the list of enzymes given below, provide all chemical structures and reactions for complete metabolism of the fatty acids 8:0, 18:145 and 12:247,10. It is unnecessary to repeat a reaction once it has been drawn out previously. Refer to the repeated reaction by group and number. Use the next pages if necessary and clearly identify which fatty acid is being metabolized.
- v Hydroxy methyl glutaryl coA Match the following metabolites with the correct metabolic pathway v Propionyl-CoA A. Kreb's cycle v Dihydroxy acetone phosphate B. Soluble fiber fermenta v succinyl co-A C. Cholesterol synthesis v Hydroxy methyl glutaryl coA D. glycolysis v Hydroxy-butyrate E. Beta oxidationMalonyl-CoA synthesized by the action of acetyl-CoA carboxylase II is primarily used:a. To synthesize fatty acidsb. To inhibit fatty acid oxidationc. Both a and bd. Neither a nor bMatch the fatty acid catabolism reaction to the enzyme responsible. Not all the reactions have to be selected, and a reaction may be used more than once. AcylCoA dehydrogenase A. Hydrates double bond between C2 and C3 - Enoyl-CoA hydratase B. Attach acyl-CoA to carnitine - B-Hydroxyacyl-CoA dehydrogenase C Catalyze double-bond relocation Thiolase D. Reduces hydroxyl group to ketone A3.A2 enoyl isomerase E. Oxidizes hydroxyl group to ketone v Methylmalonyl-COA mutase F. Catalyzes intramolecular arrangement G. Hydrates double bond between C2 and C3 - Fatty acyl-CoA synthetase v Carnitine acyltransferase H. Reduces acyl-COA L Activates a fatty acid for b-oxidation J. Generate acyl-CoA and acetyl-CoA K. Removes acyl from camitine L. Oxidizes acyl-CoA