Carbon monoxide is toxic because it binds more strongly to the iron in hemoglobin (Hb) than does O, as indicated by these approximate standard free-energy changes in blood: Hb + 0, → HbO, AG° = -70 kJ Hb + CO HBCO HЬСО AG° = -80 kJ Using these data, estimate the equilibrium constant at 298 K for the equilibrium HbO, + CO = HÜCO + O2

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Chapter1: Chemical Foundations
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Carbon monoxide is toxic because it binds more strongly to
the iron in hemoglobin (Hb) than does O, as indicated by
these approximate standard free-energy changes in blood:
Hb + 0, → HbO, AG° = -70 kJ
Hb + CO
HBCO
HЬСО
AG° = -80 kJ
Using these data, estimate the equilibrium constant at 298
K for the equilibrium
HbO, + CO =
HÜCO + O2
Transcribed Image Text:Carbon monoxide is toxic because it binds more strongly to the iron in hemoglobin (Hb) than does O, as indicated by these approximate standard free-energy changes in blood: Hb + 0, → HbO, AG° = -70 kJ Hb + CO HBCO HЬСО AG° = -80 kJ Using these data, estimate the equilibrium constant at 298 K for the equilibrium HbO, + CO = HÜCO + O2
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