Capsaicin, the active ingredient in hot peppers, creates a burning sensation because it destroys cells in the tongue releasing acid (H+) onto taste buds it causes an inflammatory response that attracts immune cells that release soluble cytokines that bind and depolarize nociceptors ○ it causes the local temperature of the exposed tissue to increase dramatically leading to depolarization of thermoreceptors it binds and opens an ion channel on nociceptors that also happens to open in response to heat
Capsaicin, the active ingredient in hot peppers, creates a burning sensation because it destroys cells in the tongue releasing acid (H+) onto taste buds it causes an inflammatory response that attracts immune cells that release soluble cytokines that bind and depolarize nociceptors ○ it causes the local temperature of the exposed tissue to increase dramatically leading to depolarization of thermoreceptors it binds and opens an ion channel on nociceptors that also happens to open in response to heat
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter6: The Peripheral Nervous System: Afferent Division; Special Senses
Section: Chapter Questions
Problem 13RE
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Question
![Capsaicin, the active ingredient in hot peppers, creates a burning sensation
because
it destroys cells in the tongue releasing acid (H+) onto taste buds
it causes an inflammatory response that attracts immune cells that release soluble
cytokines that bind and depolarize nociceptors
○ it causes the local temperature of the exposed tissue to increase dramatically leading to
depolarization of thermoreceptors
it binds and opens an ion channel on nociceptors that also happens to open in response to
heat](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fbd1e3813-29ee-4559-9532-7c63fe4cc8e7%2F39021048-c8a3-484b-a7a5-910b37f0cb6f%2Fxxab1y6l_processed.png&w=3840&q=75)
Transcribed Image Text:Capsaicin, the active ingredient in hot peppers, creates a burning sensation
because
it destroys cells in the tongue releasing acid (H+) onto taste buds
it causes an inflammatory response that attracts immune cells that release soluble
cytokines that bind and depolarize nociceptors
○ it causes the local temperature of the exposed tissue to increase dramatically leading to
depolarization of thermoreceptors
it binds and opens an ion channel on nociceptors that also happens to open in response to
heat
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