Cancer by somatic translocation (a) Relocation of an oncogene next to a novel regulatory element: Burkitt lymphoma RegMYC MYC Chr 8 Translocation Regle break point IG Chr 14 Regla MYC Translocation (b) Formation of a hybrid oncogene: chronic myologenous leukemia ABL Chr 9 Translocation break point Chr 22 BCR1 Hybrid oncogene Translocation FIGURE 17-35 The two main ways that translocations can cause cancer in a body (somatic) cell are illustrated by the cancers Burkitt lymphoma (a) and chronic myelogenous leukemia (b). The genes MYC, BCR1, and ABL are proto-oncogenes.
Cancer by somatic translocation (a) Relocation of an oncogene next to a novel regulatory element: Burkitt lymphoma RegMYC MYC Chr 8 Translocation Regle break point IG Chr 14 Regla MYC Translocation (b) Formation of a hybrid oncogene: chronic myologenous leukemia ABL Chr 9 Translocation break point Chr 22 BCR1 Hybrid oncogene Translocation FIGURE 17-35 The two main ways that translocations can cause cancer in a body (somatic) cell are illustrated by the cancers Burkitt lymphoma (a) and chronic myelogenous leukemia (b). The genes MYC, BCR1, and ABL are proto-oncogenes.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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translocation can lead to cancer. Can you think of another genetic cause of cancer?
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