c) Draw a detailed mechanism, showing the movement of all relevant electrons, of the enzymatic reduction of the ketone (1) by an enzyme using NADH as a cofactor to produce a secondary alcohol. Assume the enzyme active site provides any acidic or basic amino acid sidechains required. You can use the truncated structure of NADH for your answer to this question. € R₂ R₁ NH₂ Truncated structure of NADH

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c) Draw a detailed mechanism, showing the movement of all relevant electrons, of
the enzymatic reduction of the ketone (1) by an enzyme using NADH as a
cofactor to produce a secondary alcohol. Assume the enzyme active site
provides any acidic or basic amino acid sidechains required. You can use the
truncated structure of NADH for your answer to this question.
Ry
€
R₂
R₁
NH₂
Truncated structure of NADH
Transcribed Image Text:c) Draw a detailed mechanism, showing the movement of all relevant electrons, of the enzymatic reduction of the ketone (1) by an enzyme using NADH as a cofactor to produce a secondary alcohol. Assume the enzyme active site provides any acidic or basic amino acid sidechains required. You can use the truncated structure of NADH for your answer to this question. Ry € R₂ R₁ NH₂ Truncated structure of NADH
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