GABA, gamma-aminobutyric acid, also known as "the calming chemical", is an inhibitory neurotransmitter that blocks certain nerve signals in the brain to reduce fear, anxiety, and stress. In the cell, GABA is generated from one of the twenty natural proteinogenic amino acids through decarboxylation catalyzed by a decarboxylase enzyme. What is this precursor amino acid?

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Q: orthog

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Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.