Br Br Me₂CuLi Et₂O 1. Mg, Et₂O 2. Co 3. H3O+

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### Organic Chemistry Reaction Predictions

#### Predict the major organic product(s) of each of the following reactions. 
If multiple products are equally favored, draw them all. When necessary, indicate stereochemistry with dashes and wedges. If no reaction will occur, write “NR”.

1. **Reaction 1:**

   **Reactant:** 
   - Allyl bromide

   **Reagents:** 
   - Me₂CuLi 
   - Et₂O

   **Diagram:**
   - The image shows a structure of allyl bromide with a single arrow indicating reaction with Me₂CuLi in Et₂O.

2. **Reaction 2:**

   **Reactant:** 
   - Benzyl bromide

   **Reagents:** 
   - 1. Mg, Et₂O
   - 2. Epoxide
   - 3. H₃O⁺

   **Diagram:**
   - The image shows the structure of benzyl bromide with arrows indicating a multi-step reaction beginning with Mg in Et₂O, followed by an epoxide, and concluding with H₃O⁺.

### Propose a multistep synthetic route

**Goal:**
To accomplish the following transformations to achieve an optically pure product.

**Reactant:**
- Initial reactant: illustrated as a simple carbon chain

**Product:**
- 3-methyl-1-butanol (CH₃-CH₂-CH(OH)-CH₃)
- Optically pure

**Diagram:**
- The image shows an initial reactant with an arrow pointing towards the product (3-methyl-1-butanol) with the note 'optically pure'.

These reactions are essential in understanding the conversion of specific organic substrates into desired products using particular reagents and conditions. The student is expected to draw the major organic products and indicate stereochemistry if necessary, following the given reagents and conditions. Additionally, they should propose a synthetic route to transform the starting material into the specified optically pure product. 

Understanding the steps and mechanisms involved in these reactions is crucial for mastering organic synthesis, a key competency in organic chemistry education.
Transcribed Image Text:### Organic Chemistry Reaction Predictions #### Predict the major organic product(s) of each of the following reactions. If multiple products are equally favored, draw them all. When necessary, indicate stereochemistry with dashes and wedges. If no reaction will occur, write “NR”. 1. **Reaction 1:** **Reactant:** - Allyl bromide **Reagents:** - Me₂CuLi - Et₂O **Diagram:** - The image shows a structure of allyl bromide with a single arrow indicating reaction with Me₂CuLi in Et₂O. 2. **Reaction 2:** **Reactant:** - Benzyl bromide **Reagents:** - 1. Mg, Et₂O - 2. Epoxide - 3. H₃O⁺ **Diagram:** - The image shows the structure of benzyl bromide with arrows indicating a multi-step reaction beginning with Mg in Et₂O, followed by an epoxide, and concluding with H₃O⁺. ### Propose a multistep synthetic route **Goal:** To accomplish the following transformations to achieve an optically pure product. **Reactant:** - Initial reactant: illustrated as a simple carbon chain **Product:** - 3-methyl-1-butanol (CH₃-CH₂-CH(OH)-CH₃) - Optically pure **Diagram:** - The image shows an initial reactant with an arrow pointing towards the product (3-methyl-1-butanol) with the note 'optically pure'. These reactions are essential in understanding the conversion of specific organic substrates into desired products using particular reagents and conditions. The student is expected to draw the major organic products and indicate stereochemistry if necessary, following the given reagents and conditions. Additionally, they should propose a synthetic route to transform the starting material into the specified optically pure product. Understanding the steps and mechanisms involved in these reactions is crucial for mastering organic synthesis, a key competency in organic chemistry education.
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