Both the physical properties of the API and the excipients are essential to ensure that the formulation is physically stable and suitable for administration to patients. Discuss the general formulation considerations.The instability of emulsions may be either reversible or irreversible. Cracking indicates the extensive coalescence of the internal phase, consequently, leads to the separation of the emulsion into two distinct layers.How the cracking is occurring in the emulsions?If an emulsion has cracked will it be recovered. If yes/no discuss the phenomena.Discuss the lyophilization and appraise its importance in the pharmaceutical industry with suitable examples

Answered: Both the physical properties of the API…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

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Both the physical properties of the API and the excipients are essential to ensure that the formulation is physically stable and suitable for administration to patients. Discuss the general formulation considerations.
The instability of emulsions may be either reversible or irreversible. Cracking indicates the extensive coalescence of the internal phase, consequently, leads to the separation of the emulsion into two distinct layers.
How the cracking is occurring in the emulsions?
If an emulsion has cracked will it be recovered. If yes/no discuss the phenomena.
Discuss the lyophilization and appraise its importance in the pharmaceutical industry with suitable examples

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Physical properties of the active pharmaceutical ingredient and the excipients used to make the formulation are very important. There are many other points we need to consider before making the formulation which is used for the administration of the patient.

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