B. Consider the following types of cells and their respective conditions: i. a yeast cell undergoing fermentation but with defective alcohol dehydrogenase (hint: In yeast, alcohol dehydrogenase is responsible for shuttling reducing equivalents of cytosolic NADH to the mitochondria.)* ii. a brain cell with non-functional Complex II of the electron transport chain* * Assume that the deficiency is isolated and will not influence the function of other respiration components In these cells/tissues, determine the following from the catabolism of the 2.5 moles of the disaccharide lactose (which will be hydrolyzed first to yield glucose and galactose). (Show complete solution) a. Net ATP from glycolysis b. ATP from oxidative decarboxylation (if applicable) c. ATP formed from Krebs cycle (if applicable) d. Total net ATP
B. Consider the following types of cells and their respective conditions: i. a yeast cell undergoing fermentation but with defective alcohol dehydrogenase (hint: In yeast, alcohol dehydrogenase is responsible for shuttling reducing equivalents of cytosolic NADH to the mitochondria.)* ii. a brain cell with non-functional Complex II of the electron transport chain* * Assume that the deficiency is isolated and will not influence the function of other respiration components In these cells/tissues, determine the following from the catabolism of the 2.5 moles of the disaccharide lactose (which will be hydrolyzed first to yield glucose and galactose). (Show complete solution) a. Net ATP from glycolysis b. ATP from oxidative decarboxylation (if applicable) c. ATP formed from Krebs cycle (if applicable) d. Total net ATP
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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