Q. 3) What pathway removes uracil present in DNA? a) base excision repair b) nucleotide excision repair c) nonhomologous end joining d) translesion synthesis Q. 4) DNA polymerase uses two divalent metals, metal A and metal B for catalyzing the phosphodiester bond formation. Answer the function of metal A for this reaction. a) support the PPi release from the active site after the phosphodiester bond formation b) bring dNTP to the active site of polymerase c) decreases the pKa of 3'-OH group of primer to form an oxyanion d) increases the pKa of 3'-OH group of primer to form an oxyanion
Q. 3) What pathway removes uracil present in DNA? a) base excision repair b) nucleotide excision repair c) nonhomologous end joining d) translesion synthesis Q. 4) DNA polymerase uses two divalent metals, metal A and metal B for catalyzing the phosphodiester bond formation. Answer the function of metal A for this reaction. a) support the PPi release from the active site after the phosphodiester bond formation b) bring dNTP to the active site of polymerase c) decreases the pKa of 3'-OH group of primer to form an oxyanion d) increases the pKa of 3'-OH group of primer to form an oxyanion
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:Q. 3) What pathway removes uracil present in DNA?
a) base excision repair
b) nucleotide excision repair
c) nonhomologous end joining
d) translesion synthesis
Q. 4) DNA polymerase uses two divalent metals, metal A and metal B for catalyzing the
phosphodiester bond formation. Answer the function of metal A for this reaction.
a) support the PPi release from the active site after the phosphodiester bond formation
b) bring dNTP to the active site of polymerase
c) decreases the pKa of 3'-OH group of primer to form an oxyanion
d) increases the pKa of 3'-OH group of primer to form an oxyanion
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