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Benzodiazepines bind to GABAa receptors and increase the effects of GABA. Which effect would you predict to see after treatment with benzodiazepines? Increased influx of potassium flow. Increased G protein action. Increased influx of chloride. Increased influx of GABA.

Benzodiazepines bind to GABAa receptors and increase the effects of GABA. Which effect would you predict to see after treatment with benzodiazepines? Increased influx of potassium flow. Increased G protein action. Increased influx of chloride. Increased influx of GABA.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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### Benzodiazepines and GABAa Receptors **Question:** Benzodiazepines bind to GABA\(_{a}\) receptors and increase the effects of GABA. Which effect would you predict to see after treatment with benzodiazepines? **Options:** - ⃝ Increased influx of potassium flow. - ⃝ Increased G protein action. - ⃝ Increased influx of chloride. - ⃝ Increased influx of GABA. **Explanation:** When benzodiazepines bind to GABA\(_{a}\) receptors, they increase the effects of GABA, the primary inhibitory neurotransmitter in the central nervous system. This binding enhances the influx of chloride ions into the neuron, resulting in hyperpolarization and increased inhibitory effects, which reduces neuronal excitability. **Correct Answer:** - ⃝ Increased influx of chloride.
Transcribed Image Text:### Benzodiazepines and GABAa Receptors **Question:** Benzodiazepines bind to GABA\(_{a}\) receptors and increase the effects of GABA. Which effect would you predict to see after treatment with benzodiazepines? **Options:** - ⃝ Increased influx of potassium flow. - ⃝ Increased G protein action. - ⃝ Increased influx of chloride. - ⃝ Increased influx of GABA. **Explanation:** When benzodiazepines bind to GABA\(_{a}\) receptors, they increase the effects of GABA, the primary inhibitory neurotransmitter in the central nervous system. This binding enhances the influx of chloride ions into the neuron, resulting in hyperpolarization and increased inhibitory effects, which reduces neuronal excitability. **Correct Answer:** - ⃝ Increased influx of chloride.
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