### Benzodiazepines and GABAa Receptors**Question:**Benzodiazepines bind to GABA\(_{a}\) receptors and increase the effects of GABA. Which effect would you predict to see after treatment with benzodiazepines?**Options:**- ⃝ Increased influx of potassium flow.- ⃝ Increased G protein action.- ⃝ Increased influx of chloride.- ⃝ Increased influx of GABA.**Explanation:**When benzodiazepines bind to GABA\(_{a}\) receptors, they increase the effects of GABA, the primary inhibitory neurotransmitter in the central nervous system. This binding enhances the influx of chloride ions into the neuron, resulting in hyperpolarization and increased inhibitory effects, which reduces neuronal excitability.**Correct Answer:**- ⃝ Increased influx of chloride.

Gamma-aminobutyric acid or GABA is the inhibitory neurotransmitter of central nervous system. It…

Answered: Benzodiazepines bind to GABAa receptors…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Benzodiazepines bind to GABAa receptors and increase the effects of GABA. Which effect would you predict to see after treatment with benzodiazepines? Increased influx of potassium flow. Increased G protein action. Increased influx of chloride. Increased influx of GABA.