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Explain the feedback mechanism of the action of ADH. Copyright © McGraw-Hill Education. Permission required for reproduction or display. Stimulus Stimulus Low water intake (dehydration) High water intake (overhydration) ↑ Plasma osmolality. Į Plasma osmolality •Osmoreceptors in hypothalamus Sensor Integrating center Effector Posterior pituitary TADH JADH Kidneys tWater reabsorption Į Water reabsorption Negative Negative Less water More water feedback feedback excreted in urine excreted in urine correction correction

Explain the feedback mechanism of the action of ADH. Copyright © McGraw-Hill Education. Permission required for reproduction or display. Stimulus Stimulus Low water intake (dehydration) High water intake (overhydration) ↑ Plasma osmolality. Į Plasma osmolality •Osmoreceptors in hypothalamus Sensor Integrating center Effector Posterior pituitary TADH JADH Kidneys tWater reabsorption Į Water reabsorption Negative Negative Less water More water feedback feedback excreted in urine excreted in urine correction correction

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Explain the Feedback Mechanism of the Action of ADH** The diagram illustrates the feedback mechanism involving Antidiuretic Hormone (ADH) in response to water intake levels in the body, highlighting key processes and components. The process is divided into two scenarios: dehydration due to low water intake and overhydration due to high water intake. **Left Side: Low Water Intake (Dehydration)** 1. **Stimulus:** Low water intake leads to increased plasma osmolality. 2. **Sensor:** Osmoreceptors in the hypothalamus detect this change. 3. **Integrating Center:** The posterior pituitary gland is activated. 4. **Effector:** The kidneys. 5. **Response:** There is an increase in ADH release, leading to increased water reabsorption. 6. **Outcome:** Less water is excreted in the urine, correcting the imbalance through negative feedback. **Right Side: High Water Intake (Overhydration)** 1. **Stimulus:** High water intake results in decreased plasma osmolality. 2. **Sensor:** Osmoreceptors in the hypothalamus detect this change. 3. **Integrating Center:** The posterior pituitary gland is inhibited. 4. **Effector:** The kidneys. 5. **Response:** There is a decrease in ADH release, leading to decreased water reabsorption. 6. **Outcome:** More water is excreted in the urine, correcting the imbalance through negative feedback. **Color Coding Key:** - **Yellow Circle:** Represents sensor (osmoreceptors). - **Purple Outline:** Represents the integrating center (posterior pituitary). - **Green Outline:** Represents the effector (kidneys). This feedback mechanism helps maintain homeostasis in the body by regulating water balance through the action of ADH.
Transcribed Image Text:**Explain the Feedback Mechanism of the Action of ADH** The diagram illustrates the feedback mechanism involving Antidiuretic Hormone (ADH) in response to water intake levels in the body, highlighting key processes and components. The process is divided into two scenarios: dehydration due to low water intake and overhydration due to high water intake. **Left Side: Low Water Intake (Dehydration)** 1. **Stimulus:** Low water intake leads to increased plasma osmolality. 2. **Sensor:** Osmoreceptors in the hypothalamus detect this change. 3. **Integrating Center:** The posterior pituitary gland is activated. 4. **Effector:** The kidneys. 5. **Response:** There is an increase in ADH release, leading to increased water reabsorption. 6. **Outcome:** Less water is excreted in the urine, correcting the imbalance through negative feedback. **Right Side: High Water Intake (Overhydration)** 1. **Stimulus:** High water intake results in decreased plasma osmolality. 2. **Sensor:** Osmoreceptors in the hypothalamus detect this change. 3. **Integrating Center:** The posterior pituitary gland is inhibited. 4. **Effector:** The kidneys. 5. **Response:** There is a decrease in ADH release, leading to decreased water reabsorption. 6. **Outcome:** More water is excreted in the urine, correcting the imbalance through negative feedback. **Color Coding Key:** - **Yellow Circle:** Represents sensor (osmoreceptors). - **Purple Outline:** Represents the integrating center (posterior pituitary). - **Green Outline:** Represents the effector (kidneys). This feedback mechanism helps maintain homeostasis in the body by regulating water balance through the action of ADH.
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