Below in Figure 1 is a pedigree for a family afflicted by a genetic disorder. In some populations, Cystic fibrosis has an incidence of 1 in 2500 newborns. The carrier frequency calculated from this is 1/25. Analyze the pedigree below assuming the disease is similar to cystic fibrosis in incidence and carrier frequency. However this disease may not have the same type of genetic transmission as cystic fibrosis. What type of genetic transmission is most consistent with the pedigree? Label all the individuals that you can determine, with hypothesized genotypes. Label the individuals that have unknown genotypes with possible genotypes. Assuming her father is known to NOT be a carrier, calculate the probability that IV1 is a carrier for disease. Use the Χ2 test to determine whether your proposed transmission fits this data.
Below in Figure 1 is a pedigree for a family afflicted by a genetic disorder. In some populations, Cystic fibrosis has an incidence of 1 in 2500 newborns. The carrier frequency calculated from this is 1/25. Analyze the pedigree below assuming the disease is similar to cystic fibrosis in incidence and carrier frequency. However this disease may not have the same type of genetic transmission as cystic fibrosis. What type of genetic transmission is most consistent with the pedigree? Label all the individuals that you can determine, with hypothesized genotypes. Label the individuals that have unknown genotypes with possible genotypes. Assuming her father is known to NOT be a carrier, calculate the probability that IV1 is a carrier for disease. Use the Χ2 test to determine whether your proposed transmission fits this data.
Chapter11: Measuring Insulin Dosages
Section: Chapter Questions
Problem 1.17P
Related questions
Topic Video
Question
- Below in Figure 1 is a pedigree for a family afflicted by a genetic disorder. In some populations, Cystic fibrosis has an incidence of 1 in 2500 newborns. The carrier frequency calculated from this is 1/25. Analyze the pedigree below assuming the disease is similar to cystic fibrosis in incidence and carrier frequency. However this disease may not have the same type of genetic transmission as cystic fibrosis.
- What type of genetic transmission is most consistent with the pedigree?
- Label all the individuals that you can determine, with hypothesized genotypes.
- Label the individuals that have unknown genotypes with possible genotypes.
- Assuming her father is known to NOT be a carrier, calculate the probability that IV1 is a carrier for disease.
- Use the Χ2 test to determine whether your proposed transmission fits this data.
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 4 steps with 1 images
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
Understanding Health Insurance: A Guide to Billin…
Health & Nutrition
ISBN:
9781337679480
Author:
GREEN
Publisher:
Cengage
Understanding Health Insurance: A Guide to Billin…
Health & Nutrition
ISBN:
9781337679480
Author:
GREEN
Publisher:
Cengage