Background Problem N° 1 Objective: To explore chromosome number in living organisms and apply the definitions of ploidy: Diploid = 2n Haploid = n (as in 2n → [4n] → n+n+n+n) Monoploid = n Draparnaldia plumosa Draparnaldia acuta Polyploid = 3n, 4n, 5, 6n, - Nuclei in somatic cells of the freshwater alga Draparnaldia plumosa have 13 chromosomes. In the closely related species Draparnaldia acuta, nuclei in somatic cells have 26 chromosomes. The following is correct: a. Gametes of Draparnaldia acuta should contain 13 chromosomes. b. Droparnaldia plumosa zygotes contain 26 chromosomes; meiosis should occur after fertilization. c Draparnaldia acuta is a diploid organism; the expected n number for its haploid gametes is 13. d. Draparnaldia plumosa is a monoploid organism with n = 13. e. All of the above

Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN:9781305073951
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Chapter14: Chromosomes And Human Inheritance
Section: Chapter Questions
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**Background and Problem N° 1**

**Objective:** To explore chromosome number in living organisms and apply the definitions of ploidy:
- Diploid = 2n
- Haploid = n (as in 2n → [4n] → n + n + n + n)
- Monoploid = n
- Polyploid = 3n, 4n, 5, 6n, ...

**Images:**
- *Draparnaldia plumosa*
- *Draparnaldia acuta*

**Problem:**  
Nuclei in somatic cells of the freshwater alga *Draparnaldia plumosa* have 13 chromosomes. In the closely related species *Draparnaldia acuta*, nuclei in somatic cells have 26 chromosomes. The following is correct:
a. Gametes of *Draparnaldia acuta* should contain 13 chromosomes.
b. *Draparnaldia plumosa* zygotes contain 26 chromosomes; meiosis should occur after fertilization.
c. *Draparnaldia acuta* is a diploid organism; the expected n number for its haploid gametes is 13.
d. *Draparnaldia plumosa* is a monoploid organism with n = 13.
e. All of the above

---

**Background and Problem N° 2**

**Objective:** To explore the concept of species in sexually reproducing organisms from the perspective of hybridization.

1 pg = 10^-12 g

For some scientists, the concept of biological species focuses on the inability of organisms from distinctly different species to successfully hybridize or, if they do, the progeny is sterile (e.g., lion + tiger = liger or tion, horse + donkey = mule or hinny).

**Problem:**  
Somatic cells of the horse (*Equus caballus*) have 32 pairs of chromosomes, whereas the cells of the donkey (*Equus asinus*) have 31 pairs of chromosomes.

How many chromosomes would be expected in the somatic cells of a hybrid mule?  
Explain your answer.

---

**Background and Problem N° 3**

**Objective:** Correlate the amount of DNA with chromosome numbers in mitosis and meiosis.

**Diagram:** Cell Cycle
- G1 Phase
- S Phase
- G2 Phase
- Mitosis
- Cytokinesis

**Problem
Transcribed Image Text:**Background and Problem N° 1** **Objective:** To explore chromosome number in living organisms and apply the definitions of ploidy: - Diploid = 2n - Haploid = n (as in 2n → [4n] → n + n + n + n) - Monoploid = n - Polyploid = 3n, 4n, 5, 6n, ... **Images:** - *Draparnaldia plumosa* - *Draparnaldia acuta* **Problem:** Nuclei in somatic cells of the freshwater alga *Draparnaldia plumosa* have 13 chromosomes. In the closely related species *Draparnaldia acuta*, nuclei in somatic cells have 26 chromosomes. The following is correct: a. Gametes of *Draparnaldia acuta* should contain 13 chromosomes. b. *Draparnaldia plumosa* zygotes contain 26 chromosomes; meiosis should occur after fertilization. c. *Draparnaldia acuta* is a diploid organism; the expected n number for its haploid gametes is 13. d. *Draparnaldia plumosa* is a monoploid organism with n = 13. e. All of the above --- **Background and Problem N° 2** **Objective:** To explore the concept of species in sexually reproducing organisms from the perspective of hybridization. 1 pg = 10^-12 g For some scientists, the concept of biological species focuses on the inability of organisms from distinctly different species to successfully hybridize or, if they do, the progeny is sterile (e.g., lion + tiger = liger or tion, horse + donkey = mule or hinny). **Problem:** Somatic cells of the horse (*Equus caballus*) have 32 pairs of chromosomes, whereas the cells of the donkey (*Equus asinus*) have 31 pairs of chromosomes. How many chromosomes would be expected in the somatic cells of a hybrid mule? Explain your answer. --- **Background and Problem N° 3** **Objective:** Correlate the amount of DNA with chromosome numbers in mitosis and meiosis. **Diagram:** Cell Cycle - G1 Phase - S Phase - G2 Phase - Mitosis - Cytokinesis **Problem
**Background**

**Objective:** To use pedigrees in a case of an inherited disease in humans in order to determine the type of genetic inheritance.

According to the National Cancer Institute (NCI), “a pedigree is an illustration of family history and it shows relationships between family members and patterns of inheritance for certain traits and diseases.”

Pedigrees use standard symbols and conventions: 
- ◯ female
- □ male
- ● affected female
- ■ affected male
- ◧ proband (a.k.a. consultant, the subject of genetic studies)

Leftmost Roman numerals indicate the generation considered in the pedigree, while Arabic numerals per row indicate individuals in that particular generation, regardless of what nuclear family they are in. Combinations of Roman and Arabic numerals designate a certain individual in a particular generation (e.g., an affected female III-2 and unaffected male I-3).

- **Homozygous:** two identical alleles in both homologous chromosomes, AA, or aa.
- **Heterozygous:** different alleles on the homologous chromosomes, Aa.
- **Hemizygous:** one allele is present in one chromosome but not in the other. This can happen in sex-chromosomes, X^Y^S^, X^H^.

---

**Problem N° 4**

**Pedigree Diagram:**

- Three generations are depicted.
- Squares represent males and circles represent females.
- Shaded symbols indicate affected individuals (with myopia).

**Analyze the pedigree for myopia (nearsightedness) in a human family, depicted above.**

**Question:** What type of genetic inheritance is observed in this family for myopia?

Here are a few pointers:
- Is there a hemizygous allele, linked to the Y chromosome? ☐ Yes  ☒ No
- Is it a hemizygous allele linked to the X chromosome? ☐ Yes  ☒ No
- Is it a recessive or dominant autosomal trait? ☐ Recessive  ☐ Dominant

Assuming that myopia is determined by a single allele, use the symbols M, m and assign genotypes to all individuals on the pedigree above.

**Which individuals’ genotypes would help in distinguishing what kind of inheritance for this trait is in play here and why?** Remember that individuals are designated with the generation (Roman numeral) and the individual number (Arabic numeral), for example, I4,
Transcribed Image Text:**Background** **Objective:** To use pedigrees in a case of an inherited disease in humans in order to determine the type of genetic inheritance. According to the National Cancer Institute (NCI), “a pedigree is an illustration of family history and it shows relationships between family members and patterns of inheritance for certain traits and diseases.” Pedigrees use standard symbols and conventions: - ◯ female - □ male - ● affected female - ■ affected male - ◧ proband (a.k.a. consultant, the subject of genetic studies) Leftmost Roman numerals indicate the generation considered in the pedigree, while Arabic numerals per row indicate individuals in that particular generation, regardless of what nuclear family they are in. Combinations of Roman and Arabic numerals designate a certain individual in a particular generation (e.g., an affected female III-2 and unaffected male I-3). - **Homozygous:** two identical alleles in both homologous chromosomes, AA, or aa. - **Heterozygous:** different alleles on the homologous chromosomes, Aa. - **Hemizygous:** one allele is present in one chromosome but not in the other. This can happen in sex-chromosomes, X^Y^S^, X^H^. --- **Problem N° 4** **Pedigree Diagram:** - Three generations are depicted. - Squares represent males and circles represent females. - Shaded symbols indicate affected individuals (with myopia). **Analyze the pedigree for myopia (nearsightedness) in a human family, depicted above.** **Question:** What type of genetic inheritance is observed in this family for myopia? Here are a few pointers: - Is there a hemizygous allele, linked to the Y chromosome? ☐ Yes ☒ No - Is it a hemizygous allele linked to the X chromosome? ☐ Yes ☒ No - Is it a recessive or dominant autosomal trait? ☐ Recessive ☐ Dominant Assuming that myopia is determined by a single allele, use the symbols M, m and assign genotypes to all individuals on the pedigree above. **Which individuals’ genotypes would help in distinguishing what kind of inheritance for this trait is in play here and why?** Remember that individuals are designated with the generation (Roman numeral) and the individual number (Arabic numeral), for example, I4,
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