6,7 7:55Done Substitution Work She...Weak Nucleophile/Weak Base(ROH,H,O,RCOOH)Sw1, E1 Product mixture3.5.Methyl > 1'>216.SN2H₂CXH₂CBrOHOHStrong Nucleophile/Weak Base Strong Nucleophile/Strong BaseCN, N, Cr, Br, I, HS, HIS, RSH,HO-, RO-RNH₂, R₂PS2 Product OnlyPolar Protic Solvents Favor S1: Water (HO), formic acid (CH-0₂), hydrogen fluoride (HF), ethanol (C,H,OH), ammonia (NH), methanol (CH,OH),acetic acid (CHCOOH).Polar Aprotic Solvents favor S2: (HC-(C=O)-CH), Ethyl acetate, DMSO, dimethyl sulphoxide ((CH):S=O), DMF, N,N-dimethylformamide(CHNO), HMF (hydroxymethylfurfural), Oxolane/tetrahydrofuran (THF), crown ethers, and acetonitrile (CH,CIN)+8%CH₂CH₂CH₂K® N,DMSOⓇeNa OCH,Substitution/Elimination Reactions@ 0Na OCHⓇeNa OHSN1H₂SO4, heat3"> 2S2, E2 Product MixtureE23 2 1LTEBStrong Bulky Baset-BO, LDA, DBN, DBUE2 (Hoffman) Product OnlyE13 > 2

The given organic conversions are simple substitution or elimination reaction to give final…

Answered: -b, x OM +88 KON.C DMSO

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-b, x OM +88 KON.C DMSO

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Spectroanalytical Methods

Spectroanalytical methods measure the wavelength and intensity of radiations that are either emitted or absorbed by a molecular or atomic species. These methods are useful for evaluating the electronic or atomic arrangement of the molecules of a given analyte.

Question

6,7

7:55
Done Substitution Work She...
Weak Nucleophile/Weak Base
(ROH,H,O,RCOOH)
Sw1, E1 Product mixture
3.
5.
Methyl > 1'>21
6.
SN2
H₂C
X
H₂C
Br
OH
OH
Strong Nucleophile/Weak Base Strong Nucleophile/Strong Base
CN, N, Cr, Br, I, HS, HIS, RSH,
HO-, RO-
RNH₂, R₂P
S2 Product Only
Polar Protic Solvents Favor S1: Water (HO), formic acid (CH-0₂), hydrogen fluoride (HF), ethanol (C,H,OH), ammonia (NH), methanol (CH,OH),
acetic acid (CHCOOH).
Polar Aprotic Solvents favor S2: (HC-(C=O)-CH), Ethyl acetate, DMSO, dimethyl sulphoxide ((CH):S=O), DMF, N,N-dimethylformamide
(CHNO), HMF (hydroxymethylfurfural), Oxolane/tetrahydrofuran (THF), crown ethers, and acetonitrile (CH,CIN)
+8%
CH₂CH₂CH₂
K® N,
DMSO
Ⓡe
Na OCH,
Substitution/Elimination Reactions
@ 0
Na OCH
Ⓡe
Na OH
SN1
H₂SO4, heat
3"> 2
S2, E2 Product Mixture
E2
3 2 1
LTE
B
Strong Bulky Base
t-BO, LDA, DBN, DBU
E2 (Hoffman) Product Only
E1
3 > 2

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