AVONEX and MS. An issue of Inside MS contained an article describing AVONEX (interferon beta-1a), a drug used in the treatment of relapsing forms of multiple sclerosis (MS). Included in the article was a report on “. . . adverse events and selected laboratory abnormalities that occurred at an incidence of 2% or more among the 158 multiple sclerosis patients treated with 30 mcg of AVONEX once weekly by IM injection.” In the study, 158 patients took AVONEX and 143 patients were given placebo. a. Is this study observational or is it a designed experiment?b. Identify the treatment group, control group, and treatments

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2-Proportion Test

In a 2-proportion test, two separate proportions are measured at the same time, and their similarity is evaluated. It is also known as a 2-proportion z-test, and a comparison of two different proportions is done in this method.