(+)-Aureol is a natural product that shows selective anticancer activity against certain strains of lung cancer and colon cancer. A key step in the biosynthesis of (+)-aureol (how nature makes the molecule) is believed to involve the conversion of carbocation A to carbocation B (Org. Lett. 2012, 14, 4710-4713). HO OH HO OH

(+)-Aureol is a natural product that shows selective anticancer activity against certain strains of lung cancer and colon cancer. A key step in the biosynthesis of (+)-aureol (how nature makes the molecule) is believed to involve the conversion of carbocation A to carbocation B (Org. Lett. 2012, 14, 4710-4713). HO OH HO OH

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

C₁₂/AIC13 25 I II III IV What is the major product of the reaction shown above? A) Structure I (B) Structure | Structure III Structure IV
Provide the product and mechanism for the following reaction: 1. C12 (1 equivalent), AIBN, heat 2. 3. BH3 4. H2O2/NAOH
18. Identify the products from each step in the following synthesis sequence of reactions. Show the structure of all reactants and products from each step. (a) 3-methyl-1-pentanol + PBr3 --------> A (b) A + Mg/ether-------->B (c) B + 1.CH3CH2C(O)H/2.H3O+ -------> C (d) C + Na2Cr2O7/H2SO4, H2O -----> D
1) alkene (1 mole) 03 (1 mole) 2) (CH3)2S (1 mole) Scheme Q1a Products 1A and 1B? + (CH3)2S=O c) Assuming that in step 2 in the above reaction H2O2 (hydrogen peroxide) is used instead of (CH3)2S (dimethylsulfide), what would be the resulting products 1C and 1D? Draw their structure and circle and name the functional groups in the products.
Provide the product or reagent that completes each of the given transformations
Which of the following are the major deuterated products of the reaction below? (1) B,De. diglyme D 情 (2) H02, NAOH/H,0 HO, HO. HO. (A) (B) (C) (D) OCompounds A and D Compounds A and B O Compounds A and C Compounds B and D
Devise synthetic routes that allow you to get from the reactant/starting material side of the reactions to the product side. More than one transformation may be needed in each case. (a) H3C₂ (b) OH mayon H3C₂ OH ? ? H3C₂ H3C OH SH
Taxol is a powerful anticancer agent that was first isolated from the bark of the Pacific yew tree (Taxus brevifolia) in 1967 The structure of Taxol, shown below wasn't elucidated until 1971. Taxol prevents tumor growth by inhibiting the division C cells, or mitosis, in some types of cancer cells; and in other types of cancer cells, it induces cell death. or apoptosis. Taxol is now commonly prescribed as a treatment for breast and ovarian cancers. What functional groups are NOT present in taxol? NH OH .0.... Taxol (paclitaxel) HO Select one: O a. Aldehyde and Alcohol O b. Amide and Aldehyde Oc. Ester and Alcohol O d. Ketone and Ether O e. Carboxylic Acid and Amine OH