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- Is the chirality center R or S?Simvastatin (trade name: Zocor™M) is a pharmaceutical used to treat elevated blood lipids (i.e. high cholesterol). It contains 7 chirality centers (which allows for 128 different stereoisomers!) Determine the configuration of each chirality center. HOL. O CH3 H O H Ou yot H O XII H по / CH3Simvastatin (trade name: ZocorTM) is a pharmaceutical used to treat elevated blood lipids (i.e. high cholesterol). It contains 7 chirality centers (which allows for 128 different stereoisomers!) Determine the configuration of each chirality center. H H HO H H H H H H H H H O H H
- Assign the absolute configuration of the chirality center as R or S. CH2 HC "CH,Br C(CH3)3 F3C° R OsDetermine the configuration of the chirality center in the compound shown below OH Br ROCH3 HN- N. N. СООН Moxifloxacin Indicate the orientation around each of the labeled chirality centers in moxifloxacin. If there are only two chirality centers in the molecule choose none for the Center c.
- Use an asterisk to label each of the chirality centers in the following moleculeCount the chirality centers in each molecule below. CHO CH, ndete O 4 chiral centers O3 chiral centers O1 hiral centerAssign R or S configuration to each chirality center in the following molecules. First assign the configuration of the chirality center closest to the top of the Fischer projection. Then give the configuration of the other chirality center. CH₂OH -OH CH3CH₂ # H- -OCH3 CO₂H 1st structure: Top chirality center 2nd structure: Top chirality center H3C- H3C- OH -OH -H Other chirality center: ✓. Other chirality center: V
