As shown under each graph in this image, particular transversions (replacement of a pyrimidine by a purine of vice versa) or transitions (replacement of a purine or pyrimidine by the alternative purine or pyrimidine) are features of specific mutational signatures. Based on these data, identify the transversion or transition that seems to be induced by cigarette smoke.

Q: Most laboratory strains of E. coli contain site-specific DNA methylases. The methylase encoded by…

A: Molecular cloning is the process of making identical copies of a DNA molecule, which can be a gene,…

Q: 1. a)What would happen if the aminoacyl tRNA synthetase responsible for charging alanine tRNAs also…

A: The polymerization of amino acids according to the codons on mRNA to form proteins is known as…

Q: People with a commonly occurring, wild type allele of PTC with two adjacent thymines at a particular…

A: Part a.) :-ans.The presence of two adjacent thymines at a specific site in the PTC coding sequence…

Q: From the result shown, what might be the histidine biosynthetic pathway (the order of enzymes)?

A: Histidine biosynthesis is an ancient metabolic partway present in bacteria, archaea, lower…

Q: Describe how polymorphisms is found at 13910-C/T and 22018-G/A in the regulatory area of the lactase…

A: Lactose is the main sugar in milk, which is a disaccharide. It is hydrolyzed by intestinal lactase…

Q: 5-Bromouridine is known to induce mutations in DNA. One of the characteristics of this compound is…

A: 5-Bromouridine is a uridine subordinate with a Bromo substituent at the fifth carbon. Br -Urd is…

Q: Although a large number of mutagenic chemicals are known,none is known that induces mutations in…

A: Mutation is the process of abrupt changes in the nucleotide sequence or gene in the DNA. Mutation…

Q: Which anticodon would you predict for a tRNA speciescarrying isoleucine? Is there more than one…

A: A codon can be defined as the three-nucleotide sequence present on the DNA or RNA which codes for…

Q: If the mutation causing Tay Sachs disease involves a C to T change at position 4 in the sequence…

A: Gene probes are of three types: gene-specific probes, polymorphic probes and oligonucleotide probes.…

Q: A site-directed mutagenesis experiment was done on the catalytic triad of the serine protease…

A: Mutagenesis is that the method through that mutations in DNA molecules arise. Mutations in DNA will…

Q: What type of mutation is sickle cell anemia? Explain the molecular basis of sickle cell anemia.

A: Sickle cell anemia is an abnormal condition that arises due to the mutation in the beta-globin chain…

Q: Cystic fibrosis (CF) is an inherited disorder caused by different types of mutations, many of which…

A: CF is caused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator…

Q: 1) The plot to the right shows the Oxygen Saturation of Hemoglobin (Hb) versus O2 concentration.…

A: Oxygen saturation is a measure of how much hemoglobin is currently bound to oxygen compared to how…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.