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From the result shown, what might be the histidine biosynthetic pathway (the order of enzymes)?

From the result shown, what might be the histidine biosynthetic pathway (the order of enzymes)?

Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter9: Gene Expression And Gene Regulation
Section: Chapter Questions
Problem 18QP: The following is a portion of a protein: met-trp-tyr-arg-gly-pro-thr-Various mutant forms of this...
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**Text Transcription:** Five individual His- mutants (*hisA, hisB, hisC, hisD, and hisE*) were isolated. The genes are all involved in the histidine biosynthetic pathway. A crossfeeding experiment was carried out to determine the order of the enzymes encoded by these genes. The result is shown (A, B, C, D, and E represent the mutants *hisA, hisB, hisC, hisD,* and *hisE,* respectively). Dark area indicates bacterial growth. [o][o][o][o][o] (A) (B) (C) (D) (E) From the result shown, what might be the histidine biosynthetic pathway (the order of enzymes)? **Graph/Diagram Explanation:** The diagram consists of five circular illustrations labeled A, B, C, D, and E. Each circle contains five bars of varying lengths, and the presence of dark areas, which represent bacterial growth as a result of crossfeeding. The arrangement and shading patterns in each circle are components of the experiment's results that help determine the sequence of enzyme actions in the histidine biosynthetic pathway.
Transcribed Image Text:**Text Transcription:** Five individual His- mutants (*hisA, hisB, hisC, hisD, and hisE*) were isolated. The genes are all involved in the histidine biosynthetic pathway. A crossfeeding experiment was carried out to determine the order of the enzymes encoded by these genes. The result is shown (A, B, C, D, and E represent the mutants *hisA, hisB, hisC, hisD,* and *hisE,* respectively). Dark area indicates bacterial growth. [o][o][o][o][o] (A) (B) (C) (D) (E) From the result shown, what might be the histidine biosynthetic pathway (the order of enzymes)? **Graph/Diagram Explanation:** The diagram consists of five circular illustrations labeled A, B, C, D, and E. Each circle contains five bars of varying lengths, and the presence of dark areas, which represent bacterial growth as a result of crossfeeding. The arrangement and shading patterns in each circle are components of the experiment's results that help determine the sequence of enzyme actions in the histidine biosynthetic pathway.
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