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As part of a downstream processing sequence, 10 m³ of a process fluid containing 20 kg m an enzyme is to be concentrated to 200 kg/m³ by means of ultrafiltration. Tests have shown that the enzyme is completely retained by a 10,000 MWCO surface-modified polysulphone membrane with a filtration flux given by: of 0.04 In(250/Cf) where J is the flux in m/h and C, is the enzyme concentration in kg m-³. Four hours is available for carrying out the (a) Calculate the area of membrane needed to carry out the concentration as a simple batch process, (b) Use the following approximation for estimating the average flux during a simple batch process. process: Jav = Jf + 0.27(J; – Jf)

As part of a downstream processing sequence, 10 m³ of a process fluid containing 20 kg m an enzyme is to be concentrated to 200 kg/m³ by means of ultrafiltration. Tests have shown that the enzyme is completely retained by a 10,000 MWCO surface-modified polysulphone membrane with a filtration flux given by: of 0.04 In(250/Cf) where J is the flux in m/h and C, is the enzyme concentration in kg m-³. Four hours is available for carrying out the (a) Calculate the area of membrane needed to carry out the concentration as a simple batch process, (b) Use the following approximation for estimating the average flux during a simple batch process. process: Jav = Jf + 0.27(J; – Jf)

Introduction to Chemical Engineering Thermodynamics
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
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As part of a downstream processing sequence, 10 m³ of a process fluid containing 20 kg m-3 of an enzyme is to be concentrated to 200 kg/m³ by means of ultrafiltration. Tests have shown that the enzyme is completely retained by a 10,000 MWCO surface-modified polysulphone membrane with a filtration flux given by: J = 0.04 In(250/C;) where J is the flux in m/h and C, is the enzyme concentration in kg m-3. Four hours is available for carrying out the process. (a) Calculate the area of membrane needed to carry out the concentration as a simple batch process, (b) Use the following approximation for estimating the average flux during a simple batch process: Jav J; +0.27(J; – J;) -
Transcribed Image Text:As part of a downstream processing sequence, 10 m³ of a process fluid containing 20 kg m-3 of an enzyme is to be concentrated to 200 kg/m³ by means of ultrafiltration. Tests have shown that the enzyme is completely retained by a 10,000 MWCO surface-modified polysulphone membrane with a filtration flux given by: J = 0.04 In(250/C;) where J is the flux in m/h and C, is the enzyme concentration in kg m-3. Four hours is available for carrying out the process. (a) Calculate the area of membrane needed to carry out the concentration as a simple batch process, (b) Use the following approximation for estimating the average flux during a simple batch process: Jav J; +0.27(J; – J;) -
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