art A s a technician in a large pharmaceutical research firm, you need to produce 150. mL of 1.00 mol L-1 hosphate buffer solution of pH = 7.00. The pKa of H2PO4 is 7.21. potassium ou have the following supplies: 2.00 L of 1.00 mol L- KH2PO4 stock solution, 1.50 L of 1.00 mol L-1 K,HPC stock solution, and a carboy of pure distilled H2O. How much 1.00 mol L KH2PO4 will you need to make this solution? Express your answer to three significant digits with the appropriate units. > View Available Hint(s) HA Volume of KH2PO4 needed = Value Units Submit Previous Answers
art A s a technician in a large pharmaceutical research firm, you need to produce 150. mL of 1.00 mol L-1 hosphate buffer solution of pH = 7.00. The pKa of H2PO4 is 7.21. potassium ou have the following supplies: 2.00 L of 1.00 mol L- KH2PO4 stock solution, 1.50 L of 1.00 mol L-1 K,HPC stock solution, and a carboy of pure distilled H2O. How much 1.00 mol L KH2PO4 will you need to make this solution? Express your answer to three significant digits with the appropriate units. > View Available Hint(s) HA Volume of KH2PO4 needed = Value Units Submit Previous Answers
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Part A
As a technician in a large pharmaceutical research firm, you need to produce 150. mL of 1.00 mol L- potassium
phosphate buffer solution of pH = 7.00. The pKa of H2PO4 is 7.21.
%3D
You have the following supplies: 2.00 L of 1.00 mol L- KH2PO4 stock solution, 1.50 L of 1.00 mol L- K2HPO4
stock solution, and a carboy of pure distilled H2O.
How much 1.00 mol L KH2PO4 will you need to make this solution?
Express your answer to three significant digits with the appropriate units.
> View Available Hint(s)
HA
?
Volume of KH2PO4 needed =
Value
Units
Submit
Previous Answers
X Incorrect; Try Again; 5 attempts remaining
The Henderson-Hasselbalch equation in medicine
(ICOOoncentrations in the bloodstream are physiologically controlled to keep

Transcribed Image Text:The Henderson-Hasselbalch equation in medicine
Carbon dioxide (CO2) and bicarbonate (HCO3) concentrations in the bloodstream are physiologically controlled to keep
blood pH constant at a normal value of 7.40.
Physicians use the following modified form of the Henderson-Hasselbalch equation to track changes in blood pH:
[HCO3
pH = pKa+ log 0.030)(Pco,)
where HCO3 is given in millimoles/litre and the arterial blood partial pressure of CO2 is given in mmHg. The pKa of
carbonic acid is 6.1. Hyperventilation causes a physiological state in which the concentration of CO2 in the bloodstream
drops. The drop in the partial pressure of CO2 constricts arteries and reduces blood flow to the brain, causing dizziness or
even fainting.
Part B
If the normal physiological concentration of HCO3 is 24 mmol L-, what is the pH of blood if Pco, drops to 35.0
mmHg ?
Express your answer numerically using two decimal places.
View Available Hint(s)
Αφ
?
pH =
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