A Ramachandran Plot illustrates acceptable phi (φ) and psi (ψ) angles for amino acids in a polypeptide. What is the primary factor that restricts these angles?     The relative abundance of proline. a   The degree of side chain (R-group) interactions. b   The relative amount of inter- and intra-strand hydrogen bonding. c   Solvent entropy (hydrophobic effect) d   Steric hindrance.

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter5: Abbreviations And Systems Of Measurement
Section: Chapter Questions
Problem 12CRQ
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A Ramachandran Plot illustrates acceptable phi (φ) and psi (ψ) angles for amino acids in a polypeptide. What is the primary factor that restricts these angles?

   

The relative abundance of proline.

a  

The degree of side chain (R-group) interactions.

b  

The relative amount of inter- and intra-strand hydrogen bonding.

c  

Solvent entropy (hydrophobic effect)

d  

Steric hindrance.

180
120
60
-60
-120
-180
-180
-120
-60
60
120
180
psi
phi
Transcribed Image Text:180 120 60 -60 -120 -180 -180 -120 -60 60 120 180 psi phi
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