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21. Summarize the events that occur during the Excluation-Contraction Coupling Phase in a skeletal muscle. Practice by drawing in circled numbers in the images below to match the steps I have summarized below. Excitation-Contraction Coupling Phase: 1. When the end plate potential at the knob opens enough nearby Na VGCS on the sarcolemma, this stimulates an action potential (AP) on the sarcolemma. 2. This AP spreads down the sarcolemma and t-tubules. 3. When the AP reaches the cisterna, it twists a voltage sensitive protein called the dihydropyridine receptor (DHP receptor). The twisting physically opens a Ca*² channel called a ryanodine receptor (RyR receptor). 4. Ca¹² ions flow through the ryanodine receptor channel, out of the cisterna, and into the sarcoplasm (the cytoplasm of the skeletal muscle fiber) where they then diffuse and bind to troponin to begin the first step of muscle contraction. English (United States) CHE

21. Summarize the events that occur during the Excluation-Contraction Coupling Phase in a skeletal muscle. Practice by drawing in circled numbers in the images below to match the steps I have summarized below. Excitation-Contraction Coupling Phase: 1. When the end plate potential at the knob opens enough nearby Na VGCS on the sarcolemma, this stimulates an action potential (AP) on the sarcolemma. 2. This AP spreads down the sarcolemma and t-tubules. 3. When the AP reaches the cisterna, it twists a voltage sensitive protein called the dihydropyridine receptor (DHP receptor). The twisting physically opens a Ca*² channel called a ryanodine receptor (RyR receptor). 4. Ca¹² ions flow through the ryanodine receptor channel, out of the cisterna, and into the sarcoplasm (the cytoplasm of the skeletal muscle fiber) where they then diffuse and bind to troponin to begin the first step of muscle contraction. English (United States) CHE

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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21. Summarize the events that occur during the Excluation-Contraction Coupling Phase in a skeletal muscle. Practice by drawing in circled numbers in the images below to match the steps I have summarized below. Excitation-Contraction Coupling Phase: 1. When the end plate potential at the knob opens enough nearby Na VGCS on the sarcolemma, this stimulates an action potential (AP) on the sarcolemma. 2. This AP spreads down the sarcolemma and t-tubules. 3. When the AP reaches the cisterna, it twists a voltage sensitive protein called the dihydropyridine receptor (DHP receptor). The twisting physically opens a Ca*² channel called a ryanodine receptor (RyR receptor). 4. Ca¹² ions flow through the ryanodine receptor channel, out of the cisterna, and into the sarcoplasm (the cytoplasm of the skeletal muscle fiber) where they then diffuse and bind to troponin to begin the first step of muscle contraction. English (United States) CHE
Transcribed Image Text:21. Summarize the events that occur during the Excluation-Contraction Coupling Phase in a skeletal muscle. Practice by drawing in circled numbers in the images below to match the steps I have summarized below. Excitation-Contraction Coupling Phase: 1. When the end plate potential at the knob opens enough nearby Na VGCS on the sarcolemma, this stimulates an action potential (AP) on the sarcolemma. 2. This AP spreads down the sarcolemma and t-tubules. 3. When the AP reaches the cisterna, it twists a voltage sensitive protein called the dihydropyridine receptor (DHP receptor). The twisting physically opens a Ca*² channel called a ryanodine receptor (RyR receptor). 4. Ca¹² ions flow through the ryanodine receptor channel, out of the cisterna, and into the sarcoplasm (the cytoplasm of the skeletal muscle fiber) where they then diffuse and bind to troponin to begin the first step of muscle contraction. English (United States) CHE
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